编委
Veena Padmanaban
  • Post-Doc, The Rockefeller University
研究方向
  • Cancer Biology, Cell Biology, Molecular Biology
个人信息

教育背景

Ph.D., Johns Hopkins School of Medicine, 2019

实验室信息

Sohail Tavazoie's Lab
https://www.tavazoie-lab.org

发表论文

1. https://www.pnas.org/content/113/7/E854, 2. https://www.nature.com/articles/s41586-019-1526-3, 3. https://www.sciencedirect.com/science/article/pii/S0092867421001707, 4. https://rupress.org/jcb/article/219/9/e202001134/151934, 5. https://www.pnas.org/content/pnas/117/8/4158.full.pdf, 6. https://www.nature.com/articles/s41596-020-0335-3, 7. https://cancerres.aacrjournals.org/content/canres/80/2/204.full.pdf, 8. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007464, 9. https://www.sciencedirect.com/science/article/pii/S2211124721002060
1. Padmanaban V., Krol I., Suhail Y., Szczerba B.M., Aceto N., Bader J.S., Ewald A.J., E-cadherin is required for metastasis in multiple models of breast cancer, 2019, Nature, 573 (439-444).

2. Padmanaban V., Cheung K.J., Grasset E.M., Neumann N.M., Fraser A.K., Henriet E., Matsui W., Tran P.T., Georgess D., Ewald A.J., Organotypic culture assays for murine and human primary and metastatic-site tumors. Nature Protocols (https://doi.org/10.1038/s41596-020-0335-3).

3. Padmanaban V., Tsehay Y., Cheung K.J., Ewald A.J., Bader J.S., Between-tumor and within-tumor heterogeneity in invasive potential, 2020, PLoS Computational Biology (https://doi.org/10.1371/journal.pcbi.1007464).

4. Georgess D., Padmanaban V., Sirka O.K., Coutinho K., Choi A., Frid G., Neumann N.M., Inoue T., Ewald A.J., Twist-1 induced epithelial dissemination requires PKD1 signaling, 2020, JCB, 80 2(204-218).

5. Chan I., Knutsdottir H., Ramakrishnan G., Padmanaban V., Warrier M., Ramirez J.C., Zhang H., Jaffee E., Bader J.S., Ewald A.J., Cancer cells educate natural killer cells to a metastasis-promoting cell state, 2020, JCB 219 (9): e202001134.

6. Cheung K.J., Padmanaban V., Silvestri V., Schipper K., Cohen J.D., Fairchild A.N., Gorin M.A., Verdone J.E., Pienta K.J., Ewald A.J., Polyclonal breast cancer metastases arise from collective tumor cell clusters, 2016, PNAS. 113 7(854-863).

7. Jiao Z., Cai H., Long Y., Sirka O.K., Padmanaban V., Ewald A.J., Devreotes P.N., GGPP depletion selectively kills cells with oncogenic defects by blocking micropinocytosis, 2020, PNAS. 117 8 (4158-4168).

8. Narkar A., Johnson B., Bharne P., Zhu J., Padmanaban V., Biswas D., Fraser A., Ewald A.J., Li R., On the role of p53 in the cellular response to aneuploidy. 2021, Cell Reports. 34 (12), 108892.

9. Balamurugan K., Sehareen S., Sharan S., Krishnamurthy S., Tang W., McKennett L., Padmanaban V., Czarra K., Ewald A.J., Ueno N.T., Ambs S., Poria D.K., Sterneck E. Stabilization of E-cadherin adhesions by COX2/GSK3β signaling is a targetable pathway in metastatic breast cancer. PNAS (submitted).

10. Padmanaban V., Sirka O.K., Ewald A.J., Cellular and molecular mechanisms of cancer invasion suppression and promotion, Review for Nature Cell Biology (under revision).