TV
Tamara Vellosillo
  • Post-Doc, Carnegie Institution for Science
研究方向
  • Plant science
A Triple-challenge Mouse Model of Allergic Airway Disease, Primary Influenza Infection, and Secondary Bacterial Infection
气道变态反应性疾病,原发性流感感染,继发性细菌感染的三重小鼠模型
作者:Sean Roberts, Clare M Williams, Sreeja Roy and Yoichi Furuya日期:04/20/2020,浏览量:3199,Q&A: 0
Asthma is a global problem that affects millions of individuals. An increased risk of respiratory viral and bacterial infections is one of the complications of asthma. We recently reported that mice with ovalbumin-induced allergic airway disease (AAD) are protected against influenza-Streptococcus pneumoniae co-infection. Here, we describe in detail a protocol on how to induce AAD and influenza-S. pneumoniae co-infection in mice and to evaluate the specific roles of asthma on immunity to viral and bacterial pathogens in the hope of translating findings to benefit asthmatic individuals.