Afzal Husain, Faculty of Life Sciences, Aligarh Muslim University

Afzal Husain

Faculty, Faculty of Life Sciences, Aligarh Muslim University Aligarh

研究方向

Biochemistry, Cancer Biology, Cell Biology, Molecular Biology, Chromatin and Genome Integrity

Novel Method for Site-specific Induction of Oxidative DNA Damage to Study Recruitment of Repair Proteins to Heterochromatin and Euchromatin
研究异染色体和常染色质修复蛋白补充的特定位点诱导DNA氧化损伤新方法

作者：Leizhen Wei, Satoshi Nakajima, Arthur S. Levine and Li Lan，日期：06/05/2014，浏览量：9335，Q&A： 0

ROS-induced DNA damage is repaired in living cells within a temporal and spatial context, and chromatin structure is critical to a consideration of DNA repair processes in situ. It’s well known that chromatin remodeling factors participate ...

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Nucleosome Positioning Assay
核小体定位分析实验

作者：Zhongliang Zhao and Holger Bierhoff，日期：05/20/2017，浏览量：11093，Q&A： 0

The basic unit of chromatin is the nucleosome, a histone octamer with 147 base pairs of DNA wrapped around it. Positions of nucleosomes relative to each other and to DNA elements have a strong impact on chromatin structure and gene activity and are ...

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A Method for Extracting the Nuclear Scaffold from the Chromatin Network
一种从染色质网络中提取核骨架的方法

作者：Junjie Chen, Boon Heng Dennis Teo and Jinhua Lu，日期：04/20/2018，浏览量：6675，Q&A： 0

Each cell contains many large DNA polymers packed in a nucleus of approx. 10 μm in diameter. With histones, these DNA polymers are known to form chromatins. How chromatins further compact in the nucleus is unclear but it inevitably depends on an ...

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DNase I Chromatin Accessibility Analysis
DNaseⅠ染色质可及性分析

作者：Brook S. Nepon-Sixt and Mark G. Alexandrow，日期：12/05/2019，浏览量：4462，Q&A： 0

Chromatin consists of compacted DNA in complex with proteins and contributes to the organization of DNA and its stability. Furthermore, chromatin plays key roles in regulating cellular processes such as DNA replication, transcription, DNA repair, ...

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Isolation of Chromatin-bound Proteins from Subcellular Fractions for Biochemical Analysis
从亚细胞成分中分离用于生化分析的染色质结合蛋白

作者：Sébastien Gillotin，日期：10/05/2018，浏览量：18596，Q&A： 8

Shuttling of proteins between different cellular compartments controls their proteostasis and can contribute in some cases to regulate their activity. Biochemical analysis of chromatin-bound proteins, such as transcription factors, is often ...

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