SC
Susanna Chiocca
  • Department of Experimental Oncology, European Institute of Oncology, Italy, Italy,
研究方向
  • Cell biology
个人信息

Education

Ph.D., The University of Texas Graduate Schoool Of Biomedical Sciences, MD Anderson Cancer Center, Houston, Texas, USA, 1990

Current position

Director, Viral Control of Cellular Pathways Unit, Department of Experimental Oncology, European Institute of Oncology, Milano, Italy

Publications (since 2013)

  1. https://www.ncbi.nlm.nih.gov/pubmed/?term=chiocca+s
  2. Ravenda, P. S., Zampino, M. G., Guerini-Rocco, E., Chiocca, S., Dell'Acqua, V., Trovato, C., Biffi, R., Ribero, D., Spada, F., Cella, C. A. and Fazio, N. (2017). High-risk human papillomavirus in anal squamous cell carcinoma: a 'conservative' leading role. Ann Oncol 28(5): 1160.
  3. Alterio, D., Marvaso, G., Maffini, F., Gandini, S., Chiocca, S., Ferrari, A., Preda, L., Rocca, M. C., Lepanto, D., Fodor, C., Volpe, S., Dicuonzo, S., Laudati, A., Giugliano, G., Ansarin, M. and Jereczek-Fossa, B. A. (2017). Role of EGFR as prognostic factor in head and neck cancer patients treated with surgery and postoperative radiotherapy: proposal of a new approach behind the EGFR overexpression. Med Oncol 34(6): 107.
  4. Gheit, T., Anantharaman, D., Holzinger, D., Alemany, L., Tous, S., Lucas, E., Prabhu, P. R., Pawlita, M., Ridder, R., Rehm, S., Bogers, J., Maffini, F., Chiocca, S., Lloveras, B., Kumar, R. V., Somanathan, T., de Sanjose, S., Castellsague, X., Arbyn, M., Brennan, P., Sankaranarayanan, R., Pillai, M. R., Gangane, N., Tommasino, M. and group, H.-A. s. (2017). Role of mucosal high-risk human papillomavirus types in head and neck cancers in central India. Int J Cancer 141(1): 143-151.
  5. Mattoscio, D., Casadio, C., Miccolo, C., Maffini, F., Raimondi, A., Tacchetti, C., Gheit, T., Tagliabue, M., Galimberti, V. E., De Lorenzi, F., Pawlita, M., Chiesa, F., Ansarin, M., Tommasino, M. and Chiocca, S. (2017). Autophagy regulates UBC9 levels during viral-mediated tumorigenesis. PLoS Pathog 13(3): e1006262.
  6. Citro, S. and Chiocca, S. (2017). Assessing the Role of Paralog-Specific Sumoylation of HDAC1. Methods Mol Biol 1510: 329-337.
  7. Loponte, S., Segre, C. V., Senese, S., Miccolo, C., Santaguida, S., Deflorian, G., Citro, S., Mattoscio, D., Pisati, F., Moser, M. A., Visintin, R., Seiser, C. and Chiocca, S. (2016). Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development. Sci Rep 6: 30213.
  8. Citro, S. and Chiocca, S. (2016). Detection of Sumo Modification of Endogenous Histone Deacetylase 2 (HDAC2) in Mammalian Cells. Methods Mol Biol 1436: 15-22.
  9. Benevolo, M., Dona, M. G., Ravenda, P. S. and Chiocca, S. (2016). Anal human papillomavirus infection: prevalence, diagnosis and treatment of related lesions. Expert Rev Anti Infect Ther 14(5): 465-477.
  10. Segre, C. V., Senese, S., Loponte, S., Santaguida, S., Soffientini, P., Grigorean, G., Cinquanta, M., Ossolengo, G., Seiser, C. and Chiocca, S. (2016). A monoclonal antibody specific for prophase phosphorylation of histone deacetylase 1: a readout for early mitotic cells. MAbs 8(1): 37-42.
  11. Lovisa, S., Citro, S., Sonego, M., Dall'Acqua, A., Ranzuglia, V., Berton, S., Colombatti, A., Belletti, B., Chiocca, S., Schiappacassi, M. and Baldassarre, G. (2016). SUMOylation regulates p27Kip1 stability and localization in response to TGFbeta. J Mol Cell Biol 8(1): 17-30.
  12. Mattoscio, D. and Chiocca, S. (2015). SUMO pathway components as possible cancer biomarkers. Future Oncol 11(11): 1599-1610.
  13. Mattoscio, D., Casadio, C., Fumagalli, M., Sideri, M. and Chiocca, S. (2015). The SUMO conjugating enzyme UBC9 as a biomarker for cervical HPV infections. Ecancermedicalscience 9: 534.
  14. Ravenda, P. S., Zampino, M. G., Fazio, N., Barberis, M., Bottiglieri, L. and Chiocca, S. (2015). Human papillomavirus in anal squamous cell carcinoma: an angel rather than a devil? Ecancermedicalscience 9: 529.
  15. Ghittoni, R., Accardi, R., Chiocca, S. and Tommasino, M. (2015). Role of human papillomaviruses in carcinogenesis. Ecancermedicalscience 9: 526.
  16. Chiaradonna, F., Barozzi, I., Miccolo, C., Bucci, G., Palorini, R., Fornasari, L., Botrugno, O. A., Pruneri, G., Masullo, M., Passafaro, A., Galimberti, V. E., Fantin, V. R., Richon, V. M., Pece, S., Viale, G., Di Fiore, P. P., Draetta, G., Pelicci, P. G., Minucci, S. and Chiocca, S. (2015). Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer. Antioxid Redox Signal 23(1): 15-29.
  17. Citro, S., Miccolo, C., Meloni, L. and Chiocca, S. (2015). PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression. J Mol Cell Biol 7(2): 132-142.
  18. Avila, G. A., Ramirez, D. H., Hildenbrand, Z. L., Jacquez, P., Chiocca, S., Sun, J., Rosas-Acosta, G. and Xiao, C. (2015). Expression and in vitro functional analyses of recombinant Gam1 protein. Protein Expr Purif 105: 47-53.
  19. Elrefaey, S., Massaro, M. A., Chiocca, S., Chiesa, F. and Ansarin, M. (2014). HPV in oropharyngeal cancer: the basics to know in clinical practice. Acta Otorhinolaryngol Ital 34(5): 299-309.
  20. Everett, R. D., Chiocca, S. and Orr, A. (2014). The chicken adenovirus Gam1 protein, an inhibitor of the sumoylation pathway, partially complements ICP0-null mutant herpes simplex virus 1. J Virol 88(10): 5873-5876.
  21. Varadaraj, A., Mattoscio, D. and Chiocca, S. (2014). SUMO Ubc9 enzyme as a viral target. IUBMB Life 66(1): 27-33.
  22. Pozzebon, M. E., Varadaraj, A., Mattoscio, D., Jaffray, E. G., Miccolo, C., Galimberti, V., Tommasino, M., Hay, R. T. and Chiocca, S. (2013). BC-box protein domain-related mechanism for VHL protein degradation. Proc Natl Acad Sci U S A 110(45): 18168-18173.
  23. Newbold, A., Matthews, G. M., Bots, M., Cluse, L. A., Clarke, C. J., Banks, K. M., Cullinane, C., Bolden, J. E., Christiansen, A. J., Dickins, R. A., Miccolo, C., Chiocca, S., Kral, A. M., Ozerova, N. D., Miller, T. A., Methot, J. L., Richon, V. M., Secrist, J. P., Minucci, S. and Johnstone, R. W. (2013). Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities. Mol Cancer Ther 12(12): 2709-2721.
  24. Citro, S., Jaffray, E., Hay, R. T., Seiser, C. and Chiocca, S. (2013). A role for paralog-specific sumoylation in histone deacetylase 1 stability. J Mol Cell Biol 5(6): 416-427.
  25. Mattoscio, D., Segre, C. V. and Chiocca, S. (2013). Viral manipulation of cellular protein conjugation pathways: The SUMO lesson. World J Virol 2(2): 79-90.
  26. Santoro, F., Botrugno, O. A., Dal Zuffo, R., Pallavicini, I., Matthews, G. M., Cluse, L., Barozzi, I., Senese, S., Fornasari, L., Moretti, S., Altucci, L., Pelicci, P. G., Chiocca, S., Johnstone, R. W. and Minucci, S. (2013). A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. Blood 121(17): 3459-3468.