Education

Ph.D, Graduate School of Medicine, The University of Tokyo, Japan, 2012

Current position

Assistant professor, Department of Immunology, Yokohama City University Graduate School of Medicine, Japan

Publications

1. Ban, T., Sato, G. R., Nishiyama, A., Akiyama, A., Takasuna, M., Umehara, M., Suzuki, S., Ichino, M., Matsunaga, S., Kimura, A., Kimura, Y., Yanai, H., Miyashita, S., Kuromitsu, J., Tsukahara, K., Yoshimatsu, K., Endo, I., Yamamoto, T., Hirano, H., Ryo, A., Taniguchi, T. and Tamura, T. (2016). Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity. Immunity 45(2): 319-332.
2. Kurotaki, D., Yamamoto, M., Nishiyama, A., Uno, K., Ban, T., Ichino, M., Sasaki, H., Matsunaga, S., Yoshinari, M., Ryo, A., Nakazawa, M., Ozato, K. and Tamura, T. (2014). IRF8 inhibits C/EBPalpha activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils. Nat Commun 5: 4978.
3. Kurotaki, D., Osato, N., Nishiyama, A., Yamamoto, M., Ban, T., Sato, H., Nakabayashi, J., Umehara, M., Miyake, N., Matsumoto, N., Nakazawa, M., Ozato, K. and Tamura, T. (2013). Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood 121(10): 1839-1849.
4. Yanai, H., Ban, T. and Taniguchi, T. (2012). High-mobility group box family of proteins: ligand and sensor for innate immunity. Trends Immunol 33(12): 633-640.
5. Yanai, H., Ban, T. and Taniguchi, T. (2011). Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses. J Intern Med 270(4): 301-308.
6. Yanai, H., Chiba, S., Ban, T., Nakaima, Y., Onoe, T., Honda, K., Ohdan, H. and Taniguchi, T. (2011). Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs). Proc Natl Acad Sci U S A 108(28): 11542-11547.
7. Choi, M. K., Wang, Z., Ban, T., Yanai, H., Lu, Y., Koshiba, R., Nakaima, Y., Hangai, S., Savitsky, D., Nakasato, M., Negishi, H., Takeuchi, O., Honda, K., Akira, S., Tamura, T. and Taniguchi, T. (2009). A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA. Proc Natl Acad Sci U S A 106(42): 17870-17875.
8. Yanai, H., Ban, T., Wang, Z., Choi, M. K., Kawamura, T., Negishi, H., Nakasato, M., Lu, Y., Hangai, S., Koshiba, R., Savitsky, D., Ronfani, L., Akira, S., Bianchi, M. E., Honda, K., Tamura, T., Kodama, T. and Taniguchi, T. (2009). HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462(7269): 99-103.
9. Wang, Z., Choi, M. K., Ban, T., Yanai, H., Negishi, H., Lu, Y., Tamura, T., Takaoka, A., Nishikura, K. and Taniguchi, T. (2008). Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules. Proc Natl Acad Sci U S A 105(14): 5477-5482.
10. Takaoka, A., Wang, Z., Choi, M. K., Yanai, H., Negishi, H., Ban, T., Lu, Y., Miyagishi, M., Kodama, T., Honda, K., Ohba, Y. and Taniguchi, T. (2007). DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448(7152): 501-505.