• Holderfield M, Lee BJ, Jiang J, Tomlinson A, Seamon KJ, Mira A, Patrucco E, Goodhart G, Dilly J, Gindin Y, Dinglasan N, Wang Y, Lai LP, Cai S, Jiang L, Nasholm N, Shifrin N, Blaj C, Shah H, Evans JW, Montazer N, Lai O, Shi J, Ahler E, Quintana E, Chang S, Salvador A, Marquez A, Cregg J, Liu Y, Milin A, Chen A, Ziv TB, Parsons D, Knox JE, Klomp JE, Roth J, Rees M, Ronan M, Cuevas-Navarro A, Hu F, Lito P, Santamaria D, Aguirre AJ, Waters AM, Der CJ, Ambrogio C, Wang Z, Gill AL, Koltun ES, Smith JAM, Wildes D, Singh M. - Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. - Nature. 2024 Apr 8. doi: 10.1038/s41586-024-07205-6. Online ahead of print. PMID: 38589574

• Min Luo, Yongjian Liu, Katerina Nikolovska, Brigitte Riederer, Enrico Patrucco, Franz Hofmann, Ursula Seidler. - cGMP-dependent kinase 2, Na+/H+ exchanger NHE3, and PDZ-adaptor NHERF2 co-assemble in apical membrane microdomains – Acta Physiologica – 2024 April, https://doi.org/10.1111/apha.14125. PMID: 38533975

• Mota I, Patrucco E, Mastini C, Mahadevan NR, Thai TC, Bergaggio E, Cheong TC, Leonardi G, Karaca-Atabay E, Campisi M, Poggio T, Menotti M, Ambrogio C, Longo DL, Klaeger S, Keshishian H, Sztupinszki ZM, Szallasi Z, Keskin DB, Duke-Cohan JS, Reinhold B, Carr SA, Wu CJ, Moynihan KD, Irvine DJ, Barbie DA, Reinherz EL, Voena C, Awad MM, Blasco RB, Chiarle R. - ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer - Nat Cancer. 2023 Jul 10. doi: 10.1038/s43018-023-00591-2. Online ahead of print. PMID: 37430060

• Mastini C, Campisi M, Patrucco E, Mura G, Ferreira A, Costa C, Ambrogio C, Germena G, Martinengo C, Peola S, Mota I, Vissio E, Molinaro L, Arigoni M, Olivero M, Calogero R, Prokoph N, Tabbò F, Shoji B, Brugieres L, Geoerger B, Turner SD, Cuesta-Mateos C, D'Aliberti D, Mologni L, Piazza R, Gambacorti-Passerini C, Inghirami GG, Chiono V, Kamm RD, Hirsch E, Koch R, Weinstock DM, Aster JC, Voena C, Chiarle R. - Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma. - ci Transl Med. 2023 Jun 28;15(702):eabo3826. doi: 10.1126/scitranslmed.abo3826. Epub 2023 Jun 28. PMID: 37379367

• Nicoś M, Harbers L, Patrucco E, Kramer-Drauberg M, Zhang X, Voena C, Kowalczyk A, Bożyk A, Pęksa R, Jarosz B, Szumiło J, Simonetti M, Żuk M, Wasąg B, Reszka K, Duchnowska R, Milanowski J, Chiarle R, Bienko M, Krawczyk P, Jassem J, Ambrogio C, Crosetto N. - Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases. – JTO Clin Res Rep. 2022 Nov 11;3(12):100435. doi: 10.1016/j.jtocrr.2022.100435. eCollection 2022 Dec

• Ricciuti B, Son J, Okoro JJ, Mira A, Patrucco E, Eum Y, Wang X, Paranal R, Wang H, Lin M, Haikala HM, Li J, Xu Y, Alessi JV, Chhoeu C, Redig AJ, Köhler J, Dholakia KH, Chen Y, Richard E, Nokin MJ, Santamaria D, Gokhale PC, Awad MM, Jänne PA, Ambrogio C. - Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer. – Clinical Cancer Research 2022 Apr 14;28(8):1640-1650.
PMID: 35091439 DOI: 10.1158/1078-0432.CCR-21-2719.

• Karaca Atabay E, Mecca C, Wang Q, Ambrogio C, Mota I, Prokoph N, Mura G, Martinengo C, Patrucco E, Leonardi G, Hossa J, Pich A, Mologni L, Gambacorti-Passerini C, Brugières L, Geoerger B, Turner SD, Voena C, Cheong TC, Chiarle R. - Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma. – Blood 2022 Feb 3;139(5):717-731. DOI: 10.1182/blood.2020008136

• Pighi C, Cheong TC, Compagno M, Patrucco E, Arigoni M, Olivero M, Wang Q, López C, Bernhart SH, Grande BM, Poggio T, Langellotto F, Bonello L, Dall'Olio R, Martínez-Martín S, Molinaro L, Francia di Celle P, Whitfield JR, Soucek L, Voena C, Calogero RA, Morin RD, Staudt LM, Siebert R, Zamò A, Chiarle R. - Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma. - Blood Adv 2021 Dec 14;5(23):5239-5257. DOI: 10.1182/bloodadvances.2021005682

• Baldacci S, Grégoire V, Patrucco E, Chiarle R, Jamme P,Wasielewski E, Descarpentries C, Copin M-C, Awad MM,Cortot AB. Complete and prolonged response to anti-PD1 therapy in an ALK rearrangedlung adenocarcinoma. – Lung Cancer, 2020 (Vol 146 August 2020, Pages 366-369) PMID: 32553554 DOI: 10.1016/j.lungcan.2020.05.008

• Blasco RB*, Patrucco E*, Tai WT, Chiarle R. Comment on “ALK is a therapeutic target for lethal sepsis” – Sci Transl Med. 2018 Dec 12;10(471). PMID: 30541790

• Menotti M, Ambrogio C, Cheong TC, Pighi C, Mota I, Cassel SH, Compagno M, Wang Q, Dall'Olio R, Minero VG, Poggio T, Sharma GG, Patrucco E, Mastini C, Choudhari R, Pich A, Zamo A, Piva R, Giliani S, Mologni L, Collings CK, Kadoch C, Gambacorti-Passerini C, Notarangelo LD, Anton IM, Voena C, Chiarle R. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. - Nat Med. 2019 Jan;25(1):130-140. doi: 10.1038/s41591-018-0262-9. Epub 2018 Dec 3. PMID: 30510251

• Sharma GG, Mota I, Mologni L, Patrucco E, Gambacorti-Passerini C, Chiarle R. Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes. - Cancers (Basel). 2018 Feb 28;10(3). pii: E62. doi: 10.3390/cancers10030062. Review. PMID: 29495603

• Poomvanicha M, Matthes J, Domes K, Patrucco E, Angermeier E, Laugwitz KL, Schneider T, Hofmann F. Beta-adrenergic regulation of the heart expressing the Ser1700A/Thr1704A mutated Cav1.2 channel. - J Mol Cell Cardiol. 2017 Oct;111:10-16. doi: 10.1016/j.yjmcc.2017.07.119. Epub 2017 Aug 1.PMID: 28778765

• Domes K, Patrucco E, Loga F, Dietrich A, Birnbaumer L, Wegener JW, Hofmann F. Murine cardiac growth, TRPC channels, and cGMP kinase I - Pflugers Arch. Eur. Journ. Physiol. 2014 Dec 30. [Epub ahead of print] PMID:25547873

• Patrucco E, Domes K, Sbroggio` M, Blaich A, Schlossmann J, Desch M, Rybalkin SD, Beavo JA, Lukowski RD, Hofmann F. Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation pf AngII-induced cardiac hypertrophy and fibrosis - Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12925-9. doi: 10.1073/pnas.1414364111. Epub 2014 Aug 19.,

• Shimizu-Albergine M, Tsai LC, Patrucco E, Beavo JA. cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis. - Mol Pharmacol. 2012 Apr;81(4):556-66. Epub 2012 Jan 9.

• Adamo CM, Dai DF, Percival JM, Minami E, Willis MS, Patrucco E, Froehner SC, Beavo JA. Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy - Proc Natl Acad Sci USA (2010) Nov 2; 107(44):19079-83

• Patrucco E, Albergine MS, Santana LF, Beavo JA. Phosphodiesterase 8A (PDE8A) regulates excitationcontraction coupling in ventricular myocytes. - J Mol Cell Cardiol. (2010) Aug;49(2):330-3.

• Costa C, Barberis L, Ambrogio C, Manazza AD, Patrucco E, Azzolino O, Neilsen PO, Ciraolo E, Altruda F, Prestwich GD, Chiarle R, Wymann M, Ridley A, Hirsch E. Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma. - Proc Natl Acad Sci U S A. (2007) Sep 4;104(36):14354-9

• Lionetti V; Lisi A; Patrucco E; De Giuli P; Milazzo MG; Ceci S; Wymann M; Lena A; Gremigni V; Fanelli V; Hirsch E; Ranieri VM. Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury. – Criti Care Med. (2006) Jan;34(1):134-41.

• Vecchione C, Patrucco E, Marino G, Barberis L, Poulet R, Aretini A, Maffei A, Storto M, Azzolino O, Brancaccio M, Colussi G, Altruda F, Silengo L, Tarone G, Wymann MP, Hirsch E, Lembo G. Protection from Angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ. - Journ. Exp Med. (2005) Apr 18;201(8):1217-28.

• Alloatti G, Marcantoni A, Levi R, Gallo MP, Del Sorbo L, Patrucco E, Barberis L, Malan D, Azzolino O, Wymann M, Hirsch E, Montrucchio G. Phosphoinositide 3-kinase gamma controls autonomic regulation of the mouse heart through G(i)-independent downregulation of cAMP level. - FEBS Lett. (2005) Jan 3;579(1):133-140.

• Lupia E, Goffi A, De Giuli P, Azzolino O, Bosco O, Patrucco E, Vivaldo MC, Ricca M, Wymann MP, Hirsch E, Montrucchio G, Emanuelli G. Ablation of phosphoinositol 3-kinase γ modulates the severity of acute pancreatitis. - American Journal of Pathology (2004) Dec;165(6):2003-11

• Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, Silengo L, Altruda F, Wetzker R, Wymann MP, Lembo G, Hirsch E.PI3Kγ modulates the cardiac response to chronic pressure overload by kinase-dependent and independent effects. - Cell. (2004) Aug 6;118(3):375-87.

• Hirsch E, Wymann MP, Patrucco E, Tolosano E, Bulgarelli-Leva G, Marengo S, Rocchi M, Altruda F. Analysis of the Murine Phosphoinositide 3-Kinase γ Gene. - Gene 256 (2000).

• Tolosano E, Hirsch E, Patrucco E, Camaschella C, Navone R, Silengo L, Altruda F.Defective Recovery and Severe Renal Damage After Acute Hemolysis in Hemopexin-Deficient Mice – Blood 94,11 (1999).