SD
评审
Somenath Dutta
  • Research Associate, Duke University School of Medicine
研究方向
  • Medicine
个人信息

教育背景

Ph. D, The West Bengal University of Health Sciences, Kolkata, India, 2016

实验室信息

Olabisi Lab,
DMPI, Duke University School of Medicine
Durham, NC 27701, USA

研究方向

Kidney disease, FSGS, APOL1, iPSC, Stem Cells, Organoids

发表论文

https://pubmed.ncbi.nlm.nih.gov/?term=somenath+datta
Publications: Peer Reviewed Journals
1. Datta S, Kataria R, Zhang JY, Moore S, Petitpas K, Mohamed A, Zahler N, Pollak MR, Olabisi OA. Kidney Disease-Associated APOL1Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function. J Am Soc Nephrol. 2020 Sep;31(9):2083-2096. doi: 10.1681/ASN.2020010079.
2. Datta S, Sherva RM, De La Cruz M, Long MT, Roy P, Backman V, Chowdhury S, Roy HK. Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities. Neoplasia. 2018; 20(3): 289-294.

3. Datta S, Dasgupta D, Ghosh A, Ghosh S, Manna A, Datta S, Chatterjee M, Chowdhury A, Banerjee S. Oncogenic potential of hepatitis B virus subgenotype D1 surpasses D3: significance in the development of hepatocellular carcinoma. Carcinogenesis. 2018; 39(2): 283-292.
4. Datta S, Chowdhury S, Roy HK. Metabolism, microbiome and colorectal cancer. Aging. 2017; 9(4): 1086- 1087.
5. Banerjee P, Chakraborty A, Mondal RK, Khatun M, Datta S, Das K, Pandit P, Mukherjee S, Banerjee S, Ghosh S, Chakrabarti S, Chowdhury A, Datta S. HBV quasispecies composition in Lamivudine-failed chronic hepatitis B patients and its influence on virological response to Tenofovir-based rescue therapy.
Sci Rep. 2017; 7: 44742.
6. Ghosh A, Ghosh A, Datta S, Dasgupta D, Das S, Ray S, Gupta S, Datta S, Chowdhury A, Chatterjee R,
Mohapatra SK, Banerjee S. Hepatic miR-126 is a potential plasma biomarker for detection of hepatitis B
virus infected hepatocellular carcinoma. Int J Cancer. 2016; 138(11): 2732-44.
7. Ghosh A, Ghosh S, Dasgupta D, Ghosh A, Datta S, Sikdar N, Datta S, Chowdhury A, Banerjee S. Hepatitis
B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma. Int
J Biol Sci. 2016; 12(1): 30-41.
8. Sarkar A, Datta S, Pathak BK, Mukhopadhyay SK, Chatterjee S. Japanese encephalitis associated acute
encephalitis syndrome cases in West Bengal, India: A sero-molecular evaluation in relation to clinico-
pathological spectrum. J Med Virol. 2015; 87(8): 1258-67.
9. Datta S, Ghosh A, Dasgupta D, Ghosh A, Roychoudhury S, Roy G, Das S, Das K, Gupta S, Basu K, Basu A,
Datta S, Chowdhury A, Banerjee S. Novel point and combo-mutations in the genome of hepatitis B virus- genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.
PLoS One. 2014; 9(10): e110012.
10. Datta S, Roychoudhury S, Ghosh A, Dasgupta D, Ghosh A, Chakraborty BC, Ray S, Gupta S, Santra AK,
Datta S, Das K, Dhali GK, Chowdhury A, Banerjee S. Distinct distribution pattern of hepatitis B virus genotype C and D in liver tissue and serum of dual genotype infected liver cirrhosis and hepatocellular carcinoma patients. PLoS One. 2014; 9(7): e102573.
Selected Presentations (Published): Seminars/Conferences
1. Opeyemi Olabisi, Somenath Datta, Karen Soldano, Sarah Nystrom. Upregulated JAK-STAT signaling, and augmented potassium efflux characterize iPSC-derived podocytes of Black with APOL1-associated FSGS. ASN 2021, Kidney Week: 3606979
2. Opeyemi A. Olabisi, Somenath Datta, Jiayue Zhang, Savannah Moore, Kaitlyn M. Petitpas, Adam Mohamed, Nathan Zahler, Martin R. Pollak. APOL1 Cytoxicity Is Variant and Dose Dependent. JASN (ASN 2020) Kidney Week: PO1639.
3. Somenath Datta, Mart Dela Cruz, Sanjib Chowdhury, Hemant K. Roy. Regulation of Cancer Stem Cell Markers by CohesinSa-1 in Colorectal Cancer. Gastroenterology 2018; 154 (6), s-276.
4. Somenath Datta, Mart Dela Cruz, Sanjib Chowdhury, Hemant K. Roy. Novel Role of High Order CohesinSa-1 Single Nucleotide Polymorphisms in Regulating Obesity-Associated Colorectal Cancer. Gastroenterology 2018; 154 (6), s-650.
5. Somenath Datta, Mart Dela Cruz, Sanjib Chowdhury, Hemant K. Roy. Cohesin Sa-1 Regulates β-Catenin Signaling in Colorectal Cancer. Gastroenterology 2018; 154 (6), s-991.
6. Somenath Datta, Mart Dela Cruz, Caroline Zaworski, Sanjib Chowdhury, Hemant K. Roy. Cox-2-Reporter Activity as Surrogate Marker for Anticancer Effect of Exercise-Induced Myokine in Colorectal Cancer. Gastroenterology 2018; 154 (6), s-1065.

7. Mart Dela Cruz, Arpan Mohanty, Lynn Deng, Somenath Datta, Sanjib Chowdhury, Hemant K.Roy. Unravelling the Role of Exercise Against NAFLD: Implications of the Anti-Lipogenic Role of Myokines. Gastroenterology 2018; 154 (6), s-949.
8. Mart DeLa Cruz, Navneet Momi, Somenath Datta, Sanjib Chowdhury, Hemant K. Roy. SA1 and Colorectal Cancer: Biomarker for Obesity-Driven CRC Carcinogenesis. Gastroenterology 2017; 152 (5), s-1025.
9. Somenath Datta, Richard Sherva, Mart DeLa Cruz, Sanjib Chowdhury, Hemant K. Roy. Role of SA1 Polymorphisms in Metabolic Reprogramming in Colorectal Cancer: Implications for Racial Disparities. Gastroenterology 2017; 152 (5), s-420.
10. Navneet Momi, Sanjib Chowdhury, Priyanka Majety, Mart Dela Cruz, Ashish K.Tiwari, Somenath Datta, Hemant K.Roy. The Cohesin SA1 Regulates Early Metabolic Dysregulation in Colon Carcinogenesis. Gastroenterology 2017; 152 (5), s564-s565
11. Ashish K.Tiwari, Somenath Datta, Sanjib Chowdhury, Samuel J.Miller, Mart Dela Cruz, Hemant K.Roy, Jonathan T.Ohm. Myokines Secreted from Exercising Skeletal Muscles Profoundly Alter Secretion of Adipokines from Adipocytes: Clinical and Biological Implications. Gastroenterology 2017; 152 (5), s-827.
12. Debanjali Dasgupta, Alak Manna, Somenath Datta, Alip Ghosh, Amit Ghosh, Mitali Chatterjee, Simanti Datta, Gopal Dhali, Abhijit Chowdhury, Soma Banerjee. microRNA-124 Ameliorates Alcohol Induced Liver Injury by Restricting Multiple Components Involved in Intracellular Crosstalk. Journal of Clinical and Experimental Hepatology 2016; 6: s27-s28.
13. Debanjali Dasgupta, Somenath Datta, Alak Manna, Simanti Datta, Kausik Das, Mitali Chatterjee, Gopal Krishna Dhali, Abhijit Chowdhury, Soma Banerjee. Oncogenic Potential of Hepatitis B Virus Subgenotype D1 Surpasses D3: Significance in the Development of Hepatocellular Carcinoma. Journal of Clinical and Experimental Hepatology 2016; 6: s18.
14. Suchandrima Ghosh, Alip Ghosh, Amit Ghosh, Somenath Datta, Debanjali Dasgupta, Nilabja Sikdar, Simanti Datta, Abhijit Chowdhury, Soma Banerjee. Hepatitis B Virus X Protein Upregulates hELG1/ATAD5 Expression via E2F1 in Hepatocellular Carcinoma. Journal of Clinical and Experimental Hepatology 2015; 5: s1.
15. Amit Ghosh, Alip Ghosh, Somenath Datta, Debanjali Dasgupta, Soumyajit Das, Sukanta Ray, Subash Gupta, Simanti Datta, Abhijit Chowdhury, Saroj Mohapatra, Soma Banerjee. Hepatic miR-126 is a Potential Plasma Biomarker for Detection of Hepatitis B Virus Infected Hepatocellular Carcinoma. Journal of Clinical and Experimental Hepatology 2015; 5: s57.
16. Somenath Datta, Shrabasti roychoudhury, Alip Ghosh, simanti Datta, Abhijit Chowdhury and Soma Banerjee. Role of HBX in HBV related Hepatocarcinogenesis via regulation of telomeric shelterin proteins. The Society of Biological Chemists (India), Kolkata Chapter, SBC(I). August 23-25, 2013. Sankarpur, India.
17. Somenath Datta, Alip Ghosh, Shrabasti Roychowdhury, Amit Ghosh, Debanjali Dasgupta, Gaurav Ray, Subhas Gupta, Simanti Datta, Abhijit Chowdhury, Soma Banerjee. Integration profile, spectrum and importance of Hepatitis B Virus genotype in development of hepatocellular carcinoma. 81st Annual meeting of the Society of Biological Chemists (I). November 8-11, 2012. Kolkata, India.
18. Somenath Datta, Alip Ghosh, Debanjali Dasgupta, Amit Ghosh, Shrabasti Roychowdhury, Gaurav Ray, Subhas Gupta, Simanti Datta, Abhijit Chowdhury and Soma Banerjee. Hepatitis B Virus Related Insertional Mutagenesis in Cirrhosis Patients as an Early Genetic Change leading to Hepatocellular Carcinoma. 22nd Congress of the Asian Pacific Association for the Study of the Liver (APASL 2012), February 16-19, 2012. Taipei, Taiwan.
19. Somenath Datta, Shrabasti Roychowdhury, Alip Ghosh, Amit Ghosh, Debanjali Dasgupta, Gaurav Ray, Subhas Gupta, Simanti Datta, Abhijit Chowdhury and Soma Banerjee. Hepatitis B Virus Related Insertional Mutagenesis in Cirrhosis Patients as an Early Genetic Change leading to Hepatocellular Carcinoma. The Society of Biological Chemists (SBC): One-day symposium. 12th November, 2011. Department of Biochemistry, University of Calcutta, India.

20. Somenath Datta, Kausik Das, Alip Ghosh, Simonti Datta, Amal Santra, Abhijit Chowdhury, Soma Banerjee. Accumulated mutation(s) in the hepatitis B virus genome can serve as early determinant of hepatocellular carcinoma. 30th Annual Convention of Indian association for cancer research and International symposium on ‘’ Signalling Network and Cancer”. Feb 6-9, 2011. CSIR-IICB, India.
21. Somenath Datta, Kausik Das, Alip Ghosh, Pratap Pandit, Sumantra Sarkar, Rajib Sarkar, Dilip Bhattacharya, Simanti Datta, Amal Santra, Abhijit Chowdhury, Soma Banerjee. Analysis of cumulative mutations in basal core promoter (BCP), core and HBX gene in the progression of hepatitis B related chronic liver disease (CLD) to hepatocellular carcinoma (HCC). 50th Annual Conference of the Indian Society of Gastroenterology in Association with the Indian National Association for the study of the Liver and the society of Gastrointestinal Endoscopy of India. Dec10-12, 2009. Kolkata, India.