Education
Bachelor, University of Science and Technology of China, China, 1964
Current position
Professor, Key Laboratory of RNA Biology, Institute of Biophysics, CAS, China
Publications
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Chen, X., Hao, Y., Cui, Y., Fan, Z., He, S., Luo, J. and Chen, R. (2017). LncVar: a database of genetic variation associated with long non-coding genes. Bioinformatics 33(1): 112-118.
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Zhao, Y., Li, H., Fang, S., Kang, Y., Wu, W., Hao, Y., Li, Z., Bu, D., Sun, N., Zhang, M. Q. and Chen, R. (2016). NONCODE 2016: an informative and valuable data source of long non-coding RNAs. Nucleic Acids Res 44(D1): D203-208.
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Liu, L., Yue, H., Liu, Q., Yuan, J., Li, J., Wei, G., Chen, X., Lu, Y., Guo, M., Luo, J. and Chen, R. (2016). LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway. Oncotarget 7(13): 15787-15800.
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Cui, Y., Chen, X., Luo, H., Fan, Z., Luo, J., He, S., Yue, H., Zhang, P. and Chen, R. (2016). BioCircos.js: an interactive Circos JavaScript library for biological data visualization on web applications. Bioinformatics 32(11): 1740-1742.
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Xiao, T., Liu, L., Li, H., Sun, Y., Luo, H., Li, T., Wang, S., Dalton, S., Zhao, R. C. and Chen, R. (2015). Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPalpha. Stem Cell Reports 5(5): 856-865.
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Wang, Y., He, L., Du, Y., Zhu, P., Huang, G., Luo, J., Yan, X., Ye, B., Li, C., Xia, P., Zhang, G., Tian, Y., Chen, R. and Fan, Z. (2015). The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell Stem Cell 16(4): 413-425.
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Yuan, J., Wu, W., Xie, C., Zhao, G., Zhao, Y. and Chen, R. (2014). NPInter v2.0: an updated database of ncRNA interactions. Nucleic Acids Res 42(Database issue): D104-108.
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Li, J., Chen, Z., Tian, L., Zhou, C., He, M. Y., Gao, Y., Wang, S., Zhou, F., Shi, S., Feng, X., Sun, N., Liu, Z., Skogerboe, G., Dong, J., Yao, R., Zhao, Y., Sun, J., Zhang, B., Yu, Y., Shi, X., Luo, M., Shao, K., Li, N., Qiu, B., Tan, F., Chen, R. and He, J. (2014). LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma. Gut 63(11): 1700-1710.
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Lu, X., Wang, L., Chen, S., He, L., Yang, X., Shi, Y., Cheng, J., Zhang, L., Gu, C. C., Huang, J., Wu, T., Ma, Y., Li, J., Cao, J., Chen, J., Ge, D., Fan, Z., Li, Y., Zhao, L., Li, H., Zhou, X., Chen, L., Liu, D., Chen, J., Duan, X., Hao, Y., Wang, L., Lu, F., Liu, Z., Yao, C., Shen, C., Pu, X., Yu, L., Fang, X., Xu, L., Mu, J., Wu, X., Zheng, R., Wu, N., Zhao, Q., Li, Y., Liu, X., Wang, M., Yu, D., Hu, D., Ji, X., Guo, D., Sun, D., Wang, Q., Yang, Y., Liu, F., Mao, Q., Liang, X., Ji, J., Chen, P., Mo, X., Li, D., Chai, G., Tang, Y., Li, X., Du, Z., Liu, X., Dou, C., Yang, Z., Meng, Q., Wang, D., Wang, R., Yang, J., Schunkert, H., Samani, N. J., Kathiresan, S., Reilly, M. P., Erdmann, J., Coronary, A. D. G.-W. R., Meta-Analysis, C., Peng, X., Wu, X., Liu, D., Yang, Y., Chen, R., Qiang, B. and Gu, D. (2012). Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet 44(8): 890-894.
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Wang, Y., Chen, J., Wei, G., He, H., Zhu, X., Xiao, T., Yuan, J., Dong, B., He, S., Skogerbo, G. and Chen, R. (2011). The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression. Nucleic Acids Res 39(12): 5203-5214.
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Zhao, Y., He, S., Liu, C., Ru, S., Zha, H., Yang, Z., Yang, P., Yuan, X., Sun, S., Bu, D., Huang, J., Skogerbø, G. and Chen, R. (2008). MicroRNA regulation of messenger-like noncoding RNAs: a network of mutual microRNA control. Trends in Genetics 24: 323-327.
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He, S., Su, H., Liu, C., Skogerbo, G., He, H., He, D., Zhu, X., Liu, T., Zhao, Y. and Chen, R. (2008). MicroRNA-encoding long non-coding RNAs. BMC Genomics 9: 236.
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Aftab, M. N., He, H., Skogerbo, G. and Chen, R. (2008). Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins. BMC Genomics 9: 278.
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He, H., Wang, J., Liu, T., Liu, X. S., Li, T., Wang, Y., Qian, Z., Zheng, H., Zhu, X., Wu, T., Shi, B., Deng, W., Zhou, W., Skogerbo, G. and Chen, R. (2007). Mapping the C. elegans noncoding transcriptome with a whole-genome tiling microarray. Genome Res 17(10): 1471-1477.
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Zhang, Z., Liu, C., Skogerbo, G., Zhu, X., Lu, H., Chen, L., Shi, B., Zhang, Y., Wang, J., Wu, T. and Chen, R. (2006). Dynamic changes in subgraph preference profiles of crucial transcription factors. PLoS Comput Biol 2(5): e47.
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Zhang, Y., Li, S., Skogerbo, G., Zhang, Z., Zhu, X., Zhang, Z., Sun, S., Lu, H., Shi, B. and Chen, R. (2006). Phylophenetic properties of metabolic pathway topologies as revealed by global analysis. BMC Bioinformatics 7: 252.
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Muzny, D. M., Scherer, S. E., Kaul, R., Wang, J., Yu, J., Sudbrak, R., Buhay, C. J., Chen, R., Cree, A., Ding, Y., Dugan-Rocha, S., Gill, R., Gunaratne, P., Harris, R. A., Hawes, A. C., Hernandez, J., Hodgson, A. V., Hume, J., Jackson, A., Khan, Z. M., Kovar-Smith, C., Lewis, L. R., Lozado, R. J., Metzker, M. L., Milosavljevic, A., Miner, G. R., Morgan, M. B., Nazareth, L. V., Scott, G., Sodergren, E., Song, X. Z., Steffen, D., Wei, S., Wheeler, D. A., Wright, M. W., Worley, K. C., Yuan, Y., Zhang, Z., Adams, C. Q., Ansari-Lari, M. A., Ayele, M., Brown, M. J., Chen, G., Chen, Z., Clendenning, J., Clerc-Blankenburg, K. P., Chen, R., Chen, Z., Davis, C., Delgado, O., Dinh, H. H., Dong, W., Draper, H., Ernst, S., Fu, G., Gonzalez-Garay, M. L., Garcia, D. K., Gillett, W., Gu, J., Hao, B., Haugen, E., Havlak, P., He, X., Hennig, S., Hu, S., Huang, W., Jackson, L. R., Jacob, L. S., Kelly, S. H., Kube, M., Levy, R., Li, Z., Liu, B., Liu, J., Liu, W., Lu, J., Maheshwari, M., Nguyen, B. V., Okwuonu, G. O., Palmeiri, A., Pasternak, S., Perez, L. M., Phelps, K. A., Plopper, F. J., Qiang, B., Raymond, C., Rodriguez, R., Saenphimmachak, C., Santibanez, J., Shen, H., Shen, Y., Subramanian, S., Tabor, P. E., Verduzco, D., Waldron, L., Wang, J., Wang, J., Wang, Q., Williams, G. A., Wong, G. K., Yao, Z., Zhang, J., Zhang, X., Zhao, G., Zhou, J., Zhou, Y., Nelson, D., Lehrach, H., Reinhardt, R., Naylor, S. L., Yang, H., Olson, M., Weinstock, G. and Gibbs, R. A. (2006). The DNA sequence, annotation and analysis of human chromosome 3. Nature 440(7088): 1194-1198.
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He, H., Cai, L., Skogerbo, G., Deng, W., Liu, T., Zhu, X., Wang, Y., Jia, D., Zhang, Z., Tao, Y., Zeng, H., Aftab, M. N., Cui, Y., Liu, G. and Chen, R. (2006). Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray. Nucleic Acids Res 34(10): 2976-2983.
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Deng, W., Zhu, X., Skogerbo, G., Zhao, Y., Fu, Z., Wang, Y., He, H., Cai, L., Sun, H., Liu, C., Li, B., Bai, B., Wang, J., Jia, D., Sun, S., He, H., Cui, Y., Wang, Y., Bu, D. and Chen, R. (2006). Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res 16(1): 20-29.
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Liu, C., Bai, B., Skogerbo, G., Cai, L., Deng, W., Zhang, Y., Bu, D., Zhao, Y. and Chen, R. (2005). NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Res 33(Database issue): D112-115.
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Yu, J., Hu, S., Wang, J., Wong, G. K., Li, S., Liu, B., Deng, Y., Dai, L., Zhou, Y., Zhang, X., Cao, M., Liu, J., Sun, J., Tang, J., Chen, Y., Huang, X., Lin, W., Ye, C., Tong, W., Cong, L., Geng, J., Han, Y., Li, L., Li, W., Hu, G., Huang, X., Li, W., Li, J., Liu, Z., Li, L., Liu, J., Qi, Q., Liu, J., Li, L., Li, T., Wang, X., Lu, H., Wu, T., Zhu, M., Ni, P., Han, H., Dong, W., Ren, X., Feng, X., Cui, P., Li, X., Wang, H., Xu, X., Zhai, W., Xu, Z., Zhang, J., He, S., Zhang, J., Xu, J., Zhang, K., Zheng, X., Dong, J., Zeng, W., Tao, L., Ye, J., Tan, J., Ren, X., Chen, X., He, J., Liu, D., Tian, W., Tian, C., Xia, H., Bao, Q., Li, G., Gao, H., Cao, T., Wang, J., Zhao, W., Li, P., Chen, W., Wang, X., Zhang, Y., Hu, J., Wang, J., Liu, S., Yang, J., Zhang, G., Xiong, Y., Li, Z., Mao, L., Zhou, C., Zhu, Z., Chen, R., Hao, B., Zheng, W., Chen, S., Guo, W., Li, G., Liu, S., Tao, M., Wang, J., Zhu, L., Yuan, L. and Yang, H. (2002). A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science 296(5565): 79-92.
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Bu, D., Zhao, Y., Cai, L., Xue, H., Zhu, X., Lu, H., Zhang, J., Sun, S., Ling, L., Zhang, N., Li, G. and Chen, R. (2003). Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res 31(9): 2443-2450.
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Bao, Q., Tian, Y., Li, W., Xu, Z., Xuan, Z., Hu, S., Dong, W., Yang, J., Chen, Y., Xue, Y., Xu, Y., Lai, X., Huang, L., Dong, X., Ma, Y., Ling, L., Tan, H., Chen, R., Wang, J., Yu, J. and Yang, H. (2002). A complete sequence of the T. tengcongensis genome. Genome Res 12(5): 689-700.
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Li, W., Fang, W., Ling, L., Wang, J., Xuan, Z. and Chen, R. (2002). Phylogeny Based on Whole Genome as inferred from Complete Information Set Analysis. J Biol Phys 28(3): 439-447.