Education

Ph.D., University of Texas Houston and MD Anderson Cancer Center, Houston, Texas, 2001

Current position

Associate Professor, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS
Full Member, University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS
Full Member, Institute for Reproductive Health and Regenerative Medicine, University of Kansas Medical Center, Kansas City, KS
Graduate School Faculty, Interdisciplinary Graduate Program in Biomedical Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS

Publications

1. Elsarraj, H. S., Hong, Y., Valdez, K. E., Michaels, W., Hook, M., Smith, W. P., Chien, J., Herschkowitz, J. I., Troester, M. A., Beck, M., Inciardi, M., Gatewood, J., May, L., Cusick, T., McGinness, M., Ricci, L., Fan, F., Tawfik, O., Marks, J. R., Knapp, J. R., Yeh, H. W., Thomas, P., Carrasco, D. R., Fields, T. A., Godwin, A. K. and Behbod, F. (2015). Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. Breast Cancer Res 17: 128.
   
2. Osuala, K. O., Sameni, M., Shah, S., Aggarwal, N., Simonait, M. L., Franco, O. E., Hong, Y., Hayward, S. W., Behbod, F., Mattingly, R. R. and Sloane, B. F. (2015). Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration. BMC Cancer 15: 584.
   
3. Behbod, F. and Vivanco, M. D. (2015). Side population. Methods Mol Biol 1293: 73-81.
   
4. Zou, A., Lambert, D., Yeh, H., Yasukawa, K., Behbod, F., Fan, F. and Cheng, N. (2014). Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-beta signaling proteins. BMC Cancer 14: 781.
   
5. Elsarraj, H. S., Hong, Y., Valdez, K., Carletti, M., Salah, S. M., Raimo, M., Taverna, D., Prochasson, P., Bharadwaj, U., Tweardy, D. J., Christenson, L. K. and Behbod, F. (2013). A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance. J Cell Sci 126(Pt 11): 2446-2458.
   
6. Li, H., Duhachek-Muggy, S., Qi, Y., Hong, Y., Behbod, F. and Zolkiewska, A. (2012). An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer. Breast Cancer Res Treat 135(3): 759-769.
   
7. Yeh, H. W., Gajewski, B., Mukhopadhyay, P. and Behbod, F. (2012). The Zero-truncated Poisson with Right Censoring: an Application to Translational Breast Cancer Research. Stat Biopharm Res 4(3): 252-263.
   
8. Stecklein, S. R., Kumaraswamy, E., Behbod, F., Wang, W., Chaguturu, V., Harlan-Williams, L. M. and Jensen, R. A. (2012). BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. Proc Natl Acad Sci U S A 109(34): 13650-13655.
   
9. Borrego-Diaz, E., Terai, K., Lialyte, K., Wise, A. L., Esfandyari, T., Behbod, F., Mautner, V. F., Spyra, M., Taylor, S., Parada, L. F., Upadhyaya, M. and Farassati, F. (2012). Overactivation of Ras signaling pathway in CD133+ MPNST cells. J Neurooncol 108(3): 423-434.
   
10. Elsarraj, H. S., Stecklein, S. R., Valdez, K. and Behbod, F. (2012). Emerging functions of microRNA-146a/b in development and breast cancer: microRNA-146a/b in development and breast cancer. J Mammary Gland Biol Neoplasia 17(1): 79-87.
    
11. Behbod, F. and Rosen, J. M. (2012). Mammary gland development & breast cancer; connecting the dots by non-coding RNAs. J Mammary Gland Biol Neoplasia 17(1): 1-2.
    
12. Valdez, K. E., Fan, F., Smith, W., Allred, D. C., Medina, D. and Behbod, F. (2011). Human primary ductal carcinoma in situ (DCIS) subtype-specific pathology is preserved in a mouse intraductal (MIND) xenograft model. J Pathol 225(4): 565-573.
    
13. Kittrell, F. S., Carletti, M. Z., Kerbawy, S., Heestand, J., Xian, W., Zhang, M., Lamarca, H. L., Sonnenberg, A., Rosen, J. M., Medina, D. and Behbod, F. (2011). Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res 13(2): R41.
    
14. Pal, A., Valdez, K. E., Carletti, M. Z. and Behbod, F. (2010). Targeting the perpetrator: breast cancer stem cell therapeutics. Curr Drug Targets 11(9): 1147-1156.
    
15. LaMarca, H. L., Visbal, A. P., Creighton, C. J., Liu, H., Zhang, Y., Behbod, F. and Rosen, J. M. (2010). CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells 28(3): 535-544.
    
16. Bussard, K. M., Boulanger, C. A., Kittrell, F. S., Behbod, F., Medina, D. and Smith, G. H. (2010). Immortalized, pre-malignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA. Breast Cancer Res 12(5): R86.
    
17. Behbod, F., Kittrell, F. S., LaMarca, H., Edwards, D., Kerbawy, S., Heestand, J. C., Young, E., Mukhopadhyay, P., Yeh, H. W., Allred, D. C., Hu, M., Polyak, K., Rosen, J. M. and Medina, D. (2009). An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res 11(5): R66.
    
18. Zhang, M., Behbod, F., Atkinson, R. L., Landis, M. D., Kittrell, F., Edwards, D., Medina, D., Tsimelzon, A., Hilsenbeck, S., Green, J. E., Michalowska, A. M. and Rosen, J. M. (2008). Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res 68(12): 4674-4682.
    
19. Chen, M. S., Woodward, W. A., Behbod, F., Peddibhotla, S., Alfaro, M. P., Buchholz, T. A. and Rosen, J. M. (2007). Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci 120(Pt 3): 468-477.
    
20. Woodward, W. A., Chen, M. S., Behbod, F., Alfaro, M. P., Buchholz, T. A. and Rosen, J. M. (2007). WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A 104(2): 618-623.
    
21. Behbod, F., Xian, W., Shaw, C. A., Hilsenbeck, S. G., Tsimelzon, A. and Rosen, J. M. (2006). Transcriptional profiling of mammary gland side population cells. Stem Cells 24(4): 1065-1074.
    
22. Woodward, W. A., Chen, M. S., Behbod, F. and Rosen, J. M. (2005). On mammary stem cells. J Cell Sci 118(Pt 16): 3585-3594.
    
23. Behbod, F. and Rosen, J. M. (2005). Will cancer stem cells provide new therapeutic targets? Carcinogenesis 26(4): 703-711.
    
24. Behbod, F., Nagy, Z. S., Stepkowski, S. M., Karras, J., Johnson, C. R., Jarvis, W. D. and Kirken, R. A. (2003). Specific inhibition of Stat5a/b promotes apoptosis of IL-2-responsive primary and tumor-derived lymphoid cells. J Immunol 171(8): 3919-3927.
    
25. Welm, B., Behbod, F., Goodell, M. A. and Rosen, J. M. (2003). Isolation and characterization of functional mammary gland stem cells. Cell Prolif 36 Suppl 1: 17-32.
    
26. Stepkowski, S. M., Erwin-Cohen, R. A., Behbod, F., Wang, M. E., Qu, X., Tejpal, N., Nagy, Z. S., Kahan, B. D. and Kirken, R. A. (2002). Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin. Blood 99(2): 680-689.