教育背景

PhD

实验室信息

Terry Rabbitts' lab
https://www.icr.ac.uk/our-research/researchers-and-teams/professor-terence-rabbitts/

研究方向

My lab focuses on technology development and use of synthetic intracellular immunology for producing antibody fragments as drugs. The target focus is mutant RAS and chromosomal translocation proteins such as LMO2 in T-ALL and MYCC in Burkitt’s lymphoma plus methods to target translocation fusion proteins.
In particular, I aim to develop drugs to LMO2. This oncogenic protein comes from a gene that I originally cloned from a chromosomal translocation, and, when successful with anti-LMO2 drugs, I will have used molecular cloning and molecular biology, mouse biology and pre-clinical modelling, cell biology, chemical biology and LMO2 drug discovery to typify genotype-specific therapeutics.