C57BL/6, IFNAR–/– mice (B6.129S2-Ifnar1tm1Agt/Mmjax), C57BL/6;129 mice, and C3–/– mice (B6;129S4-C3tm1Crr/J) were obtained from the Jackson Laboratory. FcR–/– mice [C.129P2(B6)-Fcer1gtm1Rav N12] were obtained from Taconic. Mice were all female and 6 to 15 weeks in age at the time of challenge.

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