The SL and DR murine peritonitis models and resolution interval (Ri) were carried out as described (10). Briefly, mice were injected intraperitoneally with 1 ml of Zym at 1 mg per mouse or 10 mg per mouse. For the indicated experiments, 200 ng of RvDp5 (7S,17S-diHDPA, catalog no. 10546, Cayman Chemical Co., Ann Arbor, MI) or 400 ng of recombinant sFgl2 (catalog no. 5257-FL; R&D Systems, Minneapolis, MN, USA) was also injected intraperitoneally. The peritoneum was lavaged at 0, 4, 12, 24, and 48 hours after injection, and the total number of infiltrated cells was assessed using trypan blue. PMNs (CD11b+Ly6G+), monocytes, and macrophage (CD11b+Ly6G) were enumerated by light microscopy and immunofluorescent staining.