Briefly, mice received a single dose of vehicle or bleomycin (1.25 U/kg) on day 0. Five days later, these mice were randomly divided into 2 groups. One group was i.p. injected with 1 mg/kg terazosin from day 5 to day 13; another group was synchronously treated with saline and served as vehicle controls. Mice were euthanized on day 14. In later experiments, bleomycin-exposed mice were treated with terazosin or vehicle from day 10 to day 21.

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