The following clinical data was collected: age, sex, gestational age, birth weight, number of blood transfusion, weekly weight measurements, days of mechanical ventilation and oxygen administration, ROP examination results, and the incidences of necrotizing enterocolitis (NEC), bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), and sepsis. Diagnosis of ROP was conducted by pediatric ophthalmologists. Evaluations of ROP were judged as follows: none, immature, or mature vascularization. Staging of disease was performed in accordance with the International Classification of ROP [18, 19].

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