Two radiologists blinded to patients’ molecular data (LW And WH) reviewed the MR images and assessed the following tumor visual radiographic features by consensus: tumor location, crossing the midline (+/−), enhancement degree (none, mild, marked), necrosis/cyst change (none, mild, marked), and presence of peritumoral edema (none, mild, marked). Necrosis was defined as an area located within the CE region of the tumor that had no or little discernable contrast enhancement. Cystic regions were defined as homogeneous areas isointense to cerebrospinal fluid on T1w and T2w images with a thin enhancing rim on T1 postcontrast images. Classification criteria were evaluated by the VASARI scoring system. 13

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