All patients’ identifiable data was kept in a password protected computer, no patient’s data was carried in a portable memory device, only the principal investigator had access to full data, as a retrospective study with no direct implication to the subjects involved, informed consent was not required; consequently, the research team requested a waiver of consent for this study.

The study was approved by King Abdullah International Medical Research Center (KAIMRC). IRB NCBE Registration No: H-01-R-005. It was conducted in accordance with the Declaration of Helsinki.