联合作者(
Sara Cabodi Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy
1 protocol
联合评审(
Abhijjeet Mishra Abhijjeet Mishra
1 protocol

Agnieszka Pastula Umeå University Umeå
6 protocols

Alak Manna Mayo Clinic
5 protocols

Alberto Rissone National Institutes of Health
4 protocols

编委
Giusy Tornillo
  • Cardiff University
研究方向
  • 干细胞
  • 已发表 protocol 1

Education

Ph.D. in Biomedical Sciences and Human Oncology, Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy, 2012

Current position

Research Associate at European Cancer Stem Cell Research Institute (ECSCRI), Cardiff School of Biosciences, Cardiff, UK

Publications

  1. Tornillo, G., Defilippi, P. and Cabodi, S. (2014). Cas proteins: dodgy scaffolding in breast cancer. Breast Cancer Res 16(5): 443.   
  2. Fusella, F., Ferretti, R., Recupero, D., Rocca, S., Di Savino, A., Tornillo, G., Silengo, L., Turco, E., Cabodi, S., Provero, P., Pandolfi, P. P., Sapino, A., Tarone, G. and Brancaccio, M. (2014). Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway. J Pathol 234(2):152-63.
  3. Saoncella, S., Tassone, B., Deklic, E., Avolio, F., Jon, C., Tornillo, G., De Luca, E., Di Iorio, E., Piva, R., Cabodi, S., Turco, E., Paolo Pandolfi, P. and Calautti, E. (2014). Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway. Stem Cells 32(3): 754-769.
  4. Pincini, A.*, Tornillo, G.*, Orso, F., Sciortino, M., Bisaro, B., Leal Mdel, P., Lembo, A., Brizzi, M. F., Turco, E., De Pitta, C., Provero, P., Medico, E., Defilippi, P., Taverna, D. and Cabodi, S. (2013). Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Cell Cycle 12(15): 2409-2422. (*Joint first authors)
  5. Tornillo, G., Elia, A. R., Castellano, I., Spadaro, M., Bernabei, P., Bisaro, B., Camacho-Leal Mdel, P., Pincini, A., Provero, P., Sapino, A., Turco, E., Defilippi, P. and Cabodi, S. (2013). p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity. Stem Cells 31(7): 1422-1433.
  6. Bisaro, B., Montani, M., Konstantinidou, G., Marchini, C., Pietrella, L., Iezzi, M., Galie, M., Orso, F., Camporeale, A., Colombo, S. M., Di Stefano, P., Tornillo, G., Camacho-Leal, M. P., Turco, E., Taverna, D., Cabodi, S., Amici, A. and Defilippi, P. (2012). p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells. Breast Cancer Res 14(5): R137.
  7. Camacho Leal Mdel, P., Pincini, A., Tornillo, G., Fiorito, E., Bisaro, B., Di Luca, E., Turco, E., Defilippi, P. and Cabodi, S. (2012). p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF. PLoS One 7(12): e49817.
  8. D'Agostino, M., Tornillo, G., Caporaso, M. G., Barone, M. V., Ghigo, E., Bonatti, S. and Mottola, G. (2011). Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8alpha and promote its ubiquitylation and endocytosis. J Cell Sci 124(Pt 21): 3545-3556.
  9. Di Stefano, P., Leal, M. P., Tornillo, G., Bisaro, B., Repetto, D., Pincini, A., Santopietro, E., Sharma, N., Turco, E., Cabodi, S. and Defilippi, P. (2011). The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. Am J Cancer Res 1(5): 663-673.
  10. Tornillo, G., Bisaro, B., Camacho-Leal Mdel, P., Galie, M., Provero, P., Di Stefano, P., Turco, E., Defilippi, P. and Cabodi, S. (2011). p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1. Eur J Cell Biol 90(2-3): 237-248.
  11. Di Stefano, P., Leal, M. P., Tornillo, G., Bisaro, B., Repetto, D., Pincini, A., Santopietro, E., Sharma, N., Turco, E., Cabodi, S. and Defilippi, P. (2011). The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. Am J Cancer Res 1(5): 663-673.
  12. Cabodi, S.*, Tinnirello, A.*, Bisaro, B.*, Tornillo, G., del Pilar Camacho-Leal, M., Forni, G., Cojoca, R., Iezzi, M., Amici, A., Montani, M., Eva, A., Di Stefano, P., Muthuswamy, S. K., Tarone, G., Turco, E. and Defilippi, P. (2010). p130Cas is an essential transducer element in ErbB2 transformation. FASEB J 24(10): 3796-3808. (*Joint first authors)
  13. Cabodi, S., Di Stefano, P., Leal Mdel, P., Tinnirello, A., Bisaro, B., Morello, V., Damiano, L., Aramu, S., Repetto, D., Tornillo, G. and Defilippi, P. (2010). Integrins and signal transduction. Adv Exp Med Biol 674: 43-54.
已发表 protocol 1篇
3D Mammary Colony-Forming Cell Assay
3D 乳腺集落形成细胞培养方法

作者:Giusy Tornillo and Sara Cabodi日期:04/05/2014,浏览量:14401,Q&A: 0
The mammary epithelium consists of multiple phenotypically and functionally distinct cell populations, which are organized as a hierarchy of stem cells, progenitors and terminally differentiated cells. Identification of the mechanisms regulating the ...
主审 protocol 21篇
Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis
小鼠多能干细胞衍生干细胞样结构的生成:植入术后胚胎发生的体外模型

Post-implantation mammalian embryogenesis involves profound molecular, cellular, and morphogenetic changes. The study of these highly dynamic processes is complicated by the limited accessibility of in utero development. In recent years, several

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Muscle Cryoinjury and Quantification of Regenerating Myofibers in Mice
小鼠肌肉低温损伤及再生肌纤维的定量研究
作者:Yori Endo, Mehran Karvar and Indranil Sinha日期:06/05/2021,浏览量:1236,Q&A: 0

Cryoinjury, or injury due to freezing, is a method of creating reproducible, local injuries in skeletal muscle. This method allows studying the regenerative response following muscle injuries in vivo, thus enabling the evaluation of local and

...
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