联合作者(
Takemi Tanaka Stephenson Cancer Center, University of Oklahoma Health Sciences Center, USA
1 protocol

Sandra Bajana Stephenson Cancer Center, University of Oklahoma Health Sciences Center, USA
1 protocol

Shin-Ae Kang
  • Stephenson Cancer Center, University of Oklahoma Health Sciences Center, USA
研究方向
  • 癌症生物学
  • 已发表 protocol 1

Education

Ph.D., Department of Biochemistry, Yonsei University, Seoul, Republic of Korea, 2011

Current position

Research Fellow, National University of Singapore, Singapore (2015-present)

Publications

  1. Kang, S. -A., Bajana, S., Tanaka, T. (2016) In vitro flow adhesion assay for analyzing shear-resistant adhesion of metastatic cancer cells to endothelial cells. Bio-protocol 6(4): e1731
  2. Kang, S. A., Tsolmon, B., Mann, A. P., Zheng, W., Zhao, L., Zhao, Y. D., Volk, D. E., Lokesh, G. L., Morris, L., Gupta, V., Razaq, W., Rui, H., Suh, K. S., Gorenstein, D. G. and Tanaka, T. (2015). Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. Toxicol Appl Pharmacol 287(1): 86-92.
  3. Kang, S. A., Hasan, N., Mann, A. P., Zheng, W., Zhao, L., Morris, L., Zhu, W., Zhao, Y. D., Suh, K. S., Dooley, W. C., Volk, D., Gorenstein, D. G., Cristofanilli, M., Rui, H. and Tanaka, T. (2015). Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis. Mol Ther 23(6): 1044-1054.
  4. Shim, H. J., Yang, H. R., Kim, H., Kang, S. A., No, K. T., Jung, Y. H. and Lee, S. T. (2014). Discovery of (E)-5-(benzylideneamino)-1H-benzo[d]imidazol-2(3H)-one derivatives as inhibitors for PTK6. Bioorg Med Chem Lett 24(19): 4659-4663.
  5. Kang, S. A. and Lee, S. T. (2013). PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation. Biochem Biophys Res Commun 431(4): 734-739.
  6. Kang, S. A., Cho, H. S., Yoon, J. B., Chung, I. K. and Lee, S. T. (2012). Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells. Biochem J 447(2): 313-320.
  7. Kang, S. A., Lee, E. S., Yoon, H. Y., Randazzo, P. A. and Lee, S. T. (2010). PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem 285(34): 26013-26021.

已发表 protocol 1篇
In vitro Flow Adhesion Assay for Analyzing Shear-resistant Adhesion of Metastatic Cancer Cells to Endothelial Cells
体外流式粘附实验法分析转移癌细胞到内皮细胞的抗剪粘附性

作者:Shin-Ae Kang, Sandra Bajana and Takemi Tanaka日期:02/20/2016,浏览量:11128,Q&A: 1
Hematogenous metastasis is a primary cause of mortality from metastatic cancer. The shear-resistant adhesion of circulating tumor cells to the vascular endothelial cell surface under blood flow is an essential step in cell extravasation and further ...