联合作者(
Ludo Van Den Bosch Department of Neuroscience, Department of Neuroscience, Belgium
2 protocols

Peter Tompa VIB, Center for Structural Biology (CSB), Vrije Universiteit Brussel (VUB), Belgium
1 protocol

Mathias De Decker KU Leuven–University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Belgium
1 protocol
联合评审(
Alessandro Didonna University of California, San Francisco
51 protocols

Alexandros Alexandratos National and Kapodistrian University of Athens
50 protocols

Amberley D. Stephens Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge
3 protocols

Brahma Mulugu Brahma Mulugu
4 protocols

编委
Steven Boeynaems
  • Post-Doc, Stanford University
研究方向
  • 分子生物学
  • neurodegeneration - protein phase transition - tandem repeats
  • 已发表 protocol 1
课题组

教育背景

PhD, University of Leuven, 2017

实验室信息

http://www.stevenboeynaems.com

发表论文

已发表 protocol 2篇
Arginine-rich Peptides Can Actively Mediate Liquid-liquid Phase Separation
富含精氨酸的肽可以主动介导液-液相分离

作者:Steven Boeynaems, Mathias De Decker, Peter Tompa and Ludo Van Den Bosch日期:09/05/2017,浏览量:10482,Q&A: 0
Studying liquid-liquid phase separation (LLPS) of proteins provides key insights into the biogenesis of membraneless organelles and pathological protein aggregation in disease. We have established a protocol for inducing the phase separation of ...
参审 protocol 4篇
Purification and HPLC Analysis of Cell Wall Muropeptides from Caulobacter crescentus
新月形杆菌细胞壁膜多肽的纯化和HPLC分析
作者:Gabriele Stankeviciute and Eric A. Klein日期:11/05/2019,浏览量:2829,Q&A: 0
The peptidoglycan sacculus, or cell wall, is what defines bacterial cell shape. Cell wall composition can be best characterized at the molecular level by digesting the peptidoglycan murein polymer into its muropeptide subunits and quantifying the ...
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Antisense Oligodeoxynucleotide Perfusion Blocks Gene Expression of Synaptic Plasticity-related Proteins without Inducing Compensation in Hippocampal Slices
反义寡脱氧核苷酸灌注可阻突触可塑性相关蛋白在海马切片上的基因表达且无诱导补偿作用
The elucidation of the molecular mechanisms of long-term synaptic plasticity has been hindered by both the compensation that can occur after chronic loss of the core plasticity molecules and by ex vivo conditions that may not reproduce in ...
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主审 protocol 6篇
Unraveling the Physicochemical Determinants of Protein Liquid-liquid Phase Separation by Nanoscale Infrared Vibrational Spectroscopy
利用纳米尺度红外振动光谱揭示蛋白质液-液相分离的理化决定因素
作者:Francesco S. Ruggeri, Alyssa M. Miller, Michele Vendruscolo and Tuomas P. J. Knowles日期:08/20/2021,浏览量:842,Q&A: 0

The phenomenon of reversible liquid-liquid phase separation of proteins underlies the formation of membraneless organelles, which are crucial for cellular processes such as signalling and transport. In addition, it is also of great interest to

...
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A Quantitative Assay to Measure Stress Granule Association of Proteins and Peptides in Semi-permeabilized Human Cells
半透性人细胞中蛋白质和肽应激颗粒结合的定量测定
作者:Saskia Hutten and Dorothee Dormann日期:12/20/2020,浏览量:1872,Q&A: 0

Stress granules (SGs) are membrane-less organelles that form in the cytoplasm through phase separation, in response to diverse stressors. SGs contain translationally stalled mRNAs, proteins involved in translation, and various RNA-binding proteins

...
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