联合作者(
David J. Sanz Physiology, University College Cork, Ireland
1 protocol

Patrick T. Harrison
  • Department of Physiology, BioSciences Institute, University College Cork, Cork, Ireland
研究方向
  • -
  • 已发表 protocol 1
已发表 protocol 1篇
Minigene Assay to Evaluate CRISPR/Cas9-based Excision of Intronic Mutations that Cause Aberrant Splicing in Human Cells
Minigene技术评估会导致人细胞产生异常剪切的基于CRISPR/Cas9 的内含子突变切除

作者:David J. Sanz and Patrick T. Harrison日期:06/05/2019,浏览量:3802,Q&A: 0
The construction of Hybrid minigenes provides a robust and simple strategy to study the effects of disease-causing mutations on mRNA splicing when biological material from patient cells is not available. Hybrid minigenes can be used as splicing ...