联合评审(
Giusy Tornillo Cardiff University
26 protocols

Shengwen Calvin Li Children's Hospital of Orange County Research Insititute
1 protocol

评审
Nandini Mondal
  • Post-Doc, Harvard Medical School
研究方向
  • 干细胞
  • Hematopoietic stem cell homing
    Mesenchymal stem cell
    Cell surface glycoengineering
    Leukocyte migration
    Cell adhesion

教育背景

Ph.D., State University of New York at Buffalo, 2014

实验室信息

Richard D. Cummings Lab
http://harvardpeg.bwh.harvard.edu/project-1/

发表论文

1. Silva M, Martin KC, Mondal N, Sackstein R. sLeX Expression Delineates Distinct Functional Subsets of Human Blood Central and Effector Memory T Cells. J Immunol. 2020 Oct 1;205(7):1920-1932. doi: 10.4049/jimmunol.1900679. Epub 2020 Aug 31. PMID: 32868410.

2. McKitrick TR, Eris D, Mondal N, Aryal RP, McCurley N, Heimburg-Molinaro J, Cummings RD. Antibodies from Lampreys as Smart Anti-Glycan Reagents (SAGRs): Perspectives on Their Specificity, Structure, and Glyco-genomics. Biochemistry. 2020 Sep 1;59(34):3111-3122. doi: 10.1021/acs.biochem.9b01015. Epub 2020 Feb 27. PMID: 32052624.

3. Mondal N, Silva M, Castano AP, Maus MV, Sackstein R. Glycoengineering of chimeric antigen receptor (CAR) T-cells to enforce E-selectin binding. J Biol Chem. 2019 Nov 29;294(48):18465-18474. doi: 10.1074/jbc.RA119.011134. Epub 2019 Oct 18. PMID: 31628196; PMCID: PMC6885642.

4. Esposito, M., Mondal, N., Greco, T. M., Wei, Y., Spadazzi, C., Lin, S.-C., . . . Kang, Y. (2019). Bone vascular niche E-selectin induces mesenchymal–epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nature Cell Biology, 21(5), 627-639. doi:10.1038/s41556-019-0309-2

5. Mondal, N., Dykstra, B., Lee, J., Ashline, D., Reinhold, V. N., Rossi, D. J., and Sackstein, R. (2018) Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells. Journal of Biological Chemistry

6. Donnelly, C., Dykstra, B., Mondal, N., Huang, J., Kaskow, B. J., Griffin, R., Sackstein, R., and Baecher-Allan, C. (2018) Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression. Scientific Reports 8, 420

7. Stolfa, G., Mondal, N., Zhu, Y., Yu, X., Buffone Jr, A., and Neelamegham, S. (2016) Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion. Scientific Reports 6, 30392

8. Mondal, N., Stolfa, G., Antonopoulos, A., Zhu, Y., Wang, S.-S., Buffone, A., Atilla-Gokcumen, G. E., Haslam, S. M., Dell, A., and Neelamegham, S. (2016) Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin–Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arteriosclerosis, Thrombosis, and Vascular Biology 36, 718-727

9. Mondal, N., Buffone, A., Stolfa, G., Antonopoulos, A., Lau, J. T. Y., Haslam, S. M., Dell, A., and Neelamegham, S. (2015) ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. Blood 125, 687-696

10. Mondal, N., Buffone Jr, A., and Neelamegham, S. (2013) Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes. Cell Adhesion & Migration 7, 288-292

11. Buffone, A., Mondal, N., Gupta, R., McHugh, K. P., Lau, J. T. Y., and Neelamegham, S. (2013) Silencing α1,3-Fucosyltransferases in Human Leukocytes Reveals a Role for FUT9 Enzyme during E-selectin-mediated Cell Adhesion. Journal of Biological Chemistry 288, 1620-1633

12. Chinthamani, S., Odusanwo, O., Mondal, N., Nelson, J., Neelamegham, S., and Baker, O. J. (2012) Lipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium. American Journal of Physiology-Cell Physiology 302, C968-C978

13. Dayananda, K. M., Singh, I., Mondal, N., and Neelamegham, S. (2010) von Willebrand factor self-association on platelet GpIbα under hydrodynamic shear: effect on shear-induced platelet activation. Blood 116, 3990-3998
参审 protocol 2篇
Generation of the Compression-induced Dedifferentiated Adipocytes (CiDAs) Using Hypertonic Medium
使用高渗培养基压缩诱导的去分化脂肪细胞(CiDAs)的产生

Current methods to obtain mesenchymal stem cells (MSCs) involve sampling, culturing, and expanding of primary MSCs from adipose, bone marrow, and umbilical cord tissues. However, the drawbacks are the limited numbers of total cells in MSC pools, and

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Cobblestone Area-forming Cell Assay of Mouse Bone Marrow Hematopoietic Stem Cells
小鼠骨髓造血干细胞的鹅卵石样区域形成细胞测定
作者:Surya Amarachintha and Qishen Pang日期:05/05/2018,浏览量:7172,Q&A: 0
Bone Marrow Hematopoietic Stem Cells (HSCs) require bone marrow microenvironment for their maintenance and proliferation. Culture of Bone Marrow Mesenchymal Stromal Cells (MSCs) provides appropriate environmental signals for HSCs survival in vitro ...
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