联合评审(
Gal Haimovich Molecular Genetics, Weizmann Institute of Science, Israel
101 protocols

Philipp Wörsdörfer University of Würzburg
4 protocols

Xi Feng University of California, San Francisco
35 protocols

评审
Chaitali Basole
  • Research scientist, Precision Biosciences
研究方向
  • 免疫学
  • 1. Phosphodiesterases
    2. Autoimmunity
    3. Cell motility
    4. Inflammation
    5. Leukocyte adhesion
    6. Signal transduction pathways (cAMP, cGMP, MAPK etc.)
    7. Protein-protein interactions
    8. Signalosomes/signaling complexes.
    9. Cancer Immunotherapy
    10. CAR T cells

教育背景

PhD Biomedical Sciences, UConn Health, CT, USA, 2017

发表论文

https://www.ncbi.nlm.nih.gov/pubmed/?term=Basole+C
1] Basole C, Nguyen R, Lamothe K, Vang AG, Clark RB, Baillie G, Epstein PM, Brocke S. PDE8 controls CD4+ T cell motility through the PDE8A-Raf-1 kinase signaling complex. Cell Signal. 2017 Aug 26. [PMID: 28851628]
2] Vang AG*, Basole C*, Dong H, Nguyen R, Housley W, Guernsey L, Thrall R, Epstein PM, Clark RB, Brocke S. Differential expression and function of PDE8 and PDE4 in effector T cells: Implications for PDE8 as a drug target in inflammation. Front. Pharmacol. 2016 Aug 23. [PMID: 27601994] (* Co-first authors)
3] Vang AG, Housley W, Dong H, Basole C, Ben-Sasson SZ, Kream BE, Epstein PM, Clark RB, Brocke S. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J. 2013 Dec 15. [PMID: 24007532]
4] Cervantes JL, Weinerman B, Basole C, Salazar JC. TLR8: the forgotten relative revindicated. Cell Mol Immunol. 2012 Nov. [PMID: 23085951]
参审 protocol 3篇
Single Cell Migration Assay Using Human Breast Cancer MDA-MB-231 Cell Line
利用人乳腺癌MDA-MB-231细胞系进行单细胞迁移分析
作者:David M. Gau and Partha Roy日期:04/20/2020,浏览量:3650,Q&A: 0
Cell migration is a fundamental cellular process that plays a crucial role in many physioglogical and pathological processes such as wound healing or cancer metastasis. Many assays have been developed to examine cell migration, such as the wound ...
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Single-cell qPCR Assay with Massively Parallel Microfluidic System
大规模平行微流控系统用于单细胞qPCR检测
作者:Marta Prieto-Vila, Takahiro Ochiya and Yusuke Yamamoto日期:03/20/2020,浏览量:2549,Q&A: 0
The single-cell transcriptome is the set of messenger RNA molecules expressed in one cell. It is extremely variable and changes according to external, physical and biochemical conditions. Due to sensitivity shortages, most of genetic studies use ...
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