联合作者(
Riccardo Filadi University of Padova Padova
1 protocol

Federica Chiara University of Padova Padova
1 protocol

Francesco Ciscato University of Padova Padova
1 protocol

Andrea Rasola
  • Faculty, University of Padova Padova
研究方向
  • 癌症生物学
  • 1. Changes in mitochondrial energy metabolism during neoplastic transformation, with a particular focus on tumors caused by the genetic syndrome neurofibromatosis type I.
    2. Analysis of the role played by the mitochondrial chaperone TRAP1 in the tumorigenic process.
    3. Mitochondrial kinases in survival and metabolic rewiring of tumor cells.
    4. Study of the regulatory mechanisms and of the apoptotic role of the mitochondrial permeability transition pore (PTP) in neoplastic models.
  • 已发表 protocol 1

教育背景

PhD, University of Torino, Italy, 1996

实验室信息

Andrea Rasola lab
http://www.biomed.unipd.it/people/rasola-andrea/

已发表 protocol 1篇
Analysis of the Effects of Hexokinase 2 Detachment From Mitochondria-Associated Membranes with the Highly Selective Peptide HK2pep
用高选择性肽HK2pep分析己糖激酶2脱离线粒体相关膜的作用

作者:Francesco Ciscato, Federica Chiara, Riccardo Filadi and Andrea Rasola日期:07/20/2021,浏览量:1267,Q&A: 0

The crucial role of hexokinase 2 (HK2) in the metabolic rewiring of tumors is now well established, which makes it a suitable target for the design of novel therapies. However, hexokinase activity is central to glucose utilization in all tissues;

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