免疫学

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    现刊
    Electrophysiological Measurements of Isolated Blood Vessels
    离体血管的电生理测量
    作者:Samuel A Molina, Daniela Maier-Begandt, Brant E Isakson and Michael Koval日期:03/20/2022,浏览量:556,Q&A: 0
    [Abstract]

    The lumen of blood vessels is covered by endothelial cells, which regulate their permeability to ions and solutes. Endothelial permeability depends on the vascular bed and cell phenotype, and is influenced by different disease states. Most characterization of endothelial permeability has been carried out using isolated cells in culture. While

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    RNA ImmunoGenic Assay: A Method to Detect Immunogenicity of in vitro Transcribed mRNA in Human Whole Blood
    RNA ImmunoGenic分析:一种检测人全血体外转录mRNA免疫原性的方法
    [Abstract] The mRNA therapeutics is a new class of medicine to treat many various diseases. However, in vitro transcribed (IVT) mRNA triggers immune responses due to recognition by human endosomal and cytoplasmic RNA sensors, but incorporation of modified nucleosides have been shown to reduce such responses. Therefore, an assay signifying important ...