哺乳纲

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    现刊
    Measurement of Bone Metastatic Tumor Growth by a Tibial Tumorigenesis Assay
    用胫骨肿瘤发生法测定骨转移瘤的生长
    作者:Baotong Zhang, Xin Li, Wei-Ping Qian, Daqing Wu and Jin-Tang Dong日期:11/20/2021,浏览量:1787,Q&A: 0
    [Abstract]

    Bone metastasis is a frequent and lethal complication of many cancer types (i.e., prostate cancer, breast cancer, and multiple myeloma), and a cure for bone metastasis remains elusive. To recapitulate the process of bone metastasis and understand how cancer cells metastasize to bone, intracardiac injection and intracaudal arterial animal models

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    3D Co-culture System of Mouse Prostatic Wild-type Fibroblasts with Human Prostate Cancer Epithelial Cells
    小鼠前列腺野生型成纤维细胞和人前列腺癌上皮细胞的3D共培养系统
    作者:Veronica R. Placencio-Hickok, Manabu Kato and Neil A. Bhowmick日期:05/05/2019,浏览量:3942,Q&A: 0
    [Abstract] Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor progression. This was established using transgenic mouse models. Paracrine interactions between fibroblasts and epithelial cells were further interrogated using isolated 2D cell culture systems, but 3D culture systems currently being developed can better mimic ...
    A Murine Orthotopic Allograft to Model Prostate Cancer Growth and Metastasis
    使用鼠原位移植建立前列腺癌生长和转移模型
    作者:Robert M. Hughes, Brian W. Simons and Paula J. Hurley日期:02/20/2017,浏览量:9513,Q&A: 0
    [Abstract] Prostate cancer is one of the most common cancers in men in the United States. Comprehensive understanding of the biology contributing to prostate cancer will have important clinical implications. Animal models have greatly impacted our knowledge of disease and will continue to be a valuable resource for future studies. Herein, we describe a ...