联合作者(
Marco Pirazzini Department of Biomedical Sciences, University of Padova, Italy, Italy,
3 protocols

评审
Domenico Azarnia Tehran
  • Post-Doc, Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
研究方向
  • 细胞生物学
  • I received my Master’s of Science degree, summa cum laude, in Cell Biology from the University of Roma “La Sapienza” in 2012. I then joined the working group of Prof. Cesare Montecucco at the University of Padova, Department of Biomedical Sciences. My PhD work focussed on the discovery of new small-molecules inhibitors able to prevent the neuroparalytic action of botulinum neurotoxins (BoNTs). I established an innovative strategy based on the possibility to hamper different and essential intracellular steps of BoNTs mechanism of intoxication shared among the different serotypes of toxins, thus independently from their antigenicity. Moreover, I provided further details about BoNTs cellular uptake into nerve terminals that led us to identify new important process of neuronal physiology. In July 2016, I joined the lab of Prof. Volker Haucke in Berlin. My current research, as postdoctoral researcher, focuses on the molecular mechanisms and pathways involved in the endocytosis at central nerve terminals.
  • 已发表 protocol 1