联合作者(
Joan Massague Cancer Biology & Genetics, Memorial Sloan Kettering Cancer Center, United States
4 protocols

Eduard Batlle Colorectal Cancer Laboratory, Institute for Research in Biomedicine, Spain
3 protocols

Xiang H.-F. Zhang Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, USA
3 protocols

Elena Sancho Oncology Programme, Institute for Research in Biomedicine, Spain
2 protocols

María Virtudes Céspedes
  • IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Spain
研究方向
  • 癌症生物学
  • 已发表 protocol 2
已发表 protocol 2篇
Immunostaining Protocol: P-Stat3 (Xenograft and Mice)
免疫染色法:P-Smat3(磷酸化-Smad3,异种移植和小鼠)

We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context ...
Immunostaining Protocol: P-Smad2 (Xenograft and Mice)
免疫染色法:P-Smad2(磷酸化-Smad2,异种移植和小鼠)

Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 ...