Asok Mukhopadhyay
  • Superannuated, Stem Cell Biology, National Institute of Immunology
  • Hematopoiesis, regenerative medicine, liver regeneration


PhD, Indian Institute of Technology, Delhi, India, 1996


Stem Cell Biology Laboratory


(since 2004)

  1. Narayan R, Agarwal T, Mishra D, Maji S, Mohanty S, Mukhopadhyay A, Maiti TK. Ectopic vascularised bone formation by human mesenchymal stem cell microtissues in a biocompatible scaffold. Colloids Surface B: Biointerfaces 2017;160, 661-670.

  2. Akhter Z, Sharawat S, Kumar V, Kochat V, Equbal Z, Ramakrishnan M, Kumar U, Mathur S, Kumar L, Mukhopadhyay A. Aggressive serous epithelial ovarian cancer is potentially propagated by EpCAM+CD45+ phenotype. Oncogene 2017; 37, 2089-2103.

  3. Garg M, Kaur S, Banik A, Kumar V, Sarin SK, Mukhopadhyay A, Trehanpati N. Bone Marrow Endothelial Progenitor Cells Activate Hepatic Stellate Cells And Aggravate Carbon Tetrachloride Induced Liver Fibrosis in Mice via Paracrine Factors. Cell Proliferation 2017 (DOI: 10.1111/cpr.12355).

  4. Baligar P, Kochat V, Arindkar SK, Equbal Z, Mukherjee S, Patel S, Nagarajan P, Mohanty S, Teckman  JH, Mukhopadhyay A. Bone marrow stem cell therapy partially ameliorates pathological consequences in livers of mice expressing mutant human a1-Antitrypsin. Hepatology 2017; 65, 1219-1335.

  5. Khosla R, Rastogi A, Ramakrishna G, Pamecha V, Singh S, Mukhopadhyay A, Vasudevan M, Sarin SK, Trehanpati N. EpCAM+ liver cancer stem-like cells exhibiting autocrine Wnt signalling potentially originate in cirrhotic patients. Stem Cells Transl Med 2016 (DOI: 10.5966/sctm.2015-0308).

  6. Equbal Z, Mukhopadhyay A. Counting on Mesenchymal stem cells: A hope for treating Parkinson’s disease. J Stem cells Research, Reviews & Reports 2016;3:1022.

  7. Baligar P, Pokhrel S, Mukhopadhyay A. Experimental Liver Fibrosis and Intrasplenic Transplantation of CD45+ Bone Marrow Cells. Bio-protocol 2016;6:e1972.

  8. Bhattacharjee J, Das B, Sharma D, Sahay P, Jain K, Mishra A, Iyer S, Nagpal P Scaria V, Nagarajan P, Khanduri P, Mukhopadhyay A, Upadhya P. Autologous NeoHep Derived From Chronic Hepatitis B Virus Patients' Blood Monocytes by Upregulation of cMET Signaling. Stem Cells Transl Med 2016 (DOI: 10.5966/sctm.2015-0308).

  9. Roy S, Krishnan S, Kumar V, Kesurwani A, Mukhopadhyay A. Amphiregulin confers protection to murine hematopoietic progenitor cells from apoptotic death. SciTz Stem Cells: Research & Therapy 2016; 1;1001.

  10. Khatri, R., Krishnan, S., Roy, S., Chattopadhyay, S., Kumar, V. and Mukhopadhyay, A. (2016). Reactive Oxygen Species Limit the Ability of Bone Marrow Stromal Cells to Support Hematopoietic Reconstitution in Aging Mice. Stem Cells Dev 25(12): 948-958.

  11. Kumar, A., Dudhal, S., Sundari, T. A., Sunkara, M., Usman, H., Varshney, A. and Mukhopadhyay, A. (2016). Dopaminergic-primed fetal liver mesenchymal stromal-like cells can reverse parkinsonian symptoms in 6-hydroxydopamine-lesioned mice. Cytotherapy 18(3): 307-319.

  12. Baligar, P., Mukherjee, S., Kochat, V., Rastogi, A. and Mukhopadhyay, A. (2016). Molecular and Cellular Functions Distinguish Superior Therapeutic Efficiency of Bone Marrow CD45 Cells Over Mesenchymal Stem Cells in Liver Cirrhosis. Stem Cells 34(1): 135-147.

  13. Kochat, V., Kanjirakkuzhiyil, S., Baligar, P., Nagarajan, P. and Mukhopadhyay, A. (2015). Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells. Stem Cell Res Ther 6: 129.

  14. Sahu, N., Baligar, P., Midha, S., Kundu, B., Bhattacharjee, M., Mukherjee, S., Mukherjee, S., Maushart, F., Das, S., Loparic, M., Kundu, S. C., Ghosh, S. and Mukhopadhyay, A. (2015). Nonmulberry Silk Fibroin Scaffold Shows Superior Osteoconductivity Than Mulberry Silk Fibroin in Calvarial Bone Regeneration. Adv Healthc Mater 4(11): 1709-1721.

  15. Ramakrishnan, M., Mathur, S. R. and Mukhopadhyay, A. (2013). Fusion-derived epithelial cancer cells express hematopoietic markers and contribute to stem cell and migratory phenotype in ovarian carcinoma. Cancer Res 73(17): 5360-5370.

  16. Mukhopadhyay, A. (2013). Perspective on liver regeneration by bone marrow-derived stem cells-a scientific realization or a paradox. Cytotherapy 15(8): 881-892.

  17. Roy, S., Javed, S., Jain, S. K., Majumdar, S. S. and Mukhopadhyay, A. (2012). Donor hematopoietic stem cells confer long-term marrow reconstitution by self-renewal divisions exceeding to that of host cells. PLoS One 7(12): e50693.

  18. Yadav, N., Rao, S., Bhowmik, D. M. and Mukhopadhyay, A. (2012). Bone marrow cells contribute to tubular epithelium regeneration following acute kidney injury induced by mercuric chloride. Indian J Med Res 136(2): 211-220.

  19. Kaur, S., Tripathi, D., Dongre, K., Garg, V., Rooge, S., Mukopadhyay, A., Sakhuja, P. and Sarin, S. K. (2012). Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidal endothelial cells (SECs) in cirrhosis through paracrine factors. Hepatol 57(6): 1193-1198.

  20. Roy, S., Tripathy, M., Mathur, N., Jain, A. and Mukhopadhyay, A. (2012). Hypoxia improves expansion potential of human cord blood-derived hematopoietic stem cells and marrow repopulation efficiency. Eur J Haematol 88(5): 396-405.

  21. Yadav, N., Kanjirakkuzhiyil, S., Ramakrishnan, M., Das, T. K. and Mukhopadhyay, A. (2012). Factor VIII can be synthesized in hemophilia A mice liver by bone marrow progenitor cell-derived hepatocytes and sinusoidal endothelial cells. Stem Cells Dev 21(1): 110-120.

  22. Pati, S., Kalra, O. P. and Mukhopadhyay, A. (2011). Foe turned friend: multiple functional roles attributable to hyper-activating stem cell factor receptor mutant in regeneration of the haematopoietic cell compartment. Cell Prolif 44(1): 10-18.

  23. Khurana, S., Jaiswal, A. K. and Mukhopadhyay, A. (2010). Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytes. J Biol Chem 285(7): 4725-4731.

  24. Pati, S., Gurudutta, G. U., Kalra, O. P. and Mukhopadhyay, A. (2010). The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): an in silico analysis. BMC Res Notes 3: 14.

  25. Yadav, N., Kanjirakkuzhiyil, S., Kumar, S., Jain, M., Halder, A., Saxena, R. and Mukhopadhyay, A. (2009). The therapeutic effect of bone marrow-derived liver cells in the phenotypic correction of murine hemophilia A. Blood 114(20): 4552-4561.

  26. Singh, K., Srivastava, A., Mathur, N., Kumar, S., Kumar, L., Mukhopadhyay, A. and Konchupillai, V. (2009). Evaluation of four methods for processing human cord blood and subsequent study of the expansion of progenitor stem cells isolated using the best method. Cytotherapy 11(6): 768-777.

  27. Khurana, S. and Mukhopadhyay, A. (2008). Hematopoietic progenitors from early murine fetal liver possess hepatic differentiation potential. Am J Pathol 173(6): 1818-1827.

  28. Khurana, S. and Mukhopadhyay, A. (2008). In vitro transdifferentiation of adult hematopoietic stem cells: an alternative source of engraftable hepatocytes. J Hepatol 49(6): 998-1007.

  29. Khurana, S. and Mukhopadhyay, A. (2007). Characterization of the potential subpopulation of bone marrow cells involved in the repair of injured liver tissue. Stem Cells 25(6): 1439-1447.

  30. Mangla, A., Khare, A., Vineeth, V., Panday, N. N., Mukhopadhyay, A., Ravindran, B., Bal, V., George, A. and Rath, S. (2004). Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses. Blood 104(4): 1191-1197.

  31. Madhusudhan, T., Majumdar, S. S. and Mukhopadhyay, A. (2004). Degeneration of stroma reduces retention of homed cells in bone marrow of lethally irradiated mice. Stem Cells Dev 13(2): 173-182.