Education
Ph.D. in Food Science, Cornell University, NY, 1999
Current position
Professor, School of Mechanical Engineering and Department of Global Biomedical Engineering, Sungkyunkwan University, Korea
Publications
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Cheong, F. C., Wong, C. C., Gao, Y., Nai, M. H., Cui, Y., Park, S., Kenney, L. J. and Lim, C. T. (2015). Rapid, high-throughput tracking of bacterial motility in 3D via phase-contrast holographic video microscopy. Biophys J 108(5): 1248-1256.
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Cui, Y., Hameed, F. M., Yang, B., Lee, K., Pan, C. Q., Park, S.* and Sheetz, M.* (2015). Cyclic stretching of soft substrates induces spreading and growth. Nat Commun 6: 6333. (IF=10.742)
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van Noort, D., Park, S. and Ngyuen, N.* (2014). Towards human on a chip: Recent progress and future perspective. Micro and Nanosystems 6, 215-231.
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Kim, S. H., Chi, M., Yi, B., Kim, S. H., Oh, S., Kim, Y., Park, S. and Sung, J. H. (2014). Three-dimensional intestinal villi epithelium enhances protection of human intestinal cells from bacterial infection by inducing mucin expression. Integr Biol (Camb) 6(12): 1122-1131.(IF=4.132)
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Shumi, Hossain, Md. A., Park, D. J., Park, S.* (2014). Inhibitory effects of green tea polyphenol epigallocatechin gallate (EGCG) on exopolysaccharide production by Streptococcus mutans under microfluidic conditions. Biochip J 8, 179-186. (IF=1.015)
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Lee, J. H., Hwang, K. A., Park, S., Choo, Y. K., Ko, K.*(2014). Expression of recombinant anti-breast cancer immunotherapeutic monoclonal antibody in baculovirus-insect cells. Entomol Res 44: 207-214.
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Kim, I. Y., Park, S. H., Kim, H., Park, S.*, Ruoff, R. S. and Hwang, S.-J. (2014). Strongly-coupled freestanding hybrid films of graphene and layered titanate nanosheets: an effective way to tailor the physicochemical and antibacterial properties of graphene film. Adv Func Mater 28:2288-2294. (IF=9.765) (Cover)
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Jang, M., Park, S., Lee, N. Y.* (2014). Polycarbonate bonding assisted by surface chemical modification without plasma treatment and its application for the construction of plastic-based cell arrays. Sens. Actuator-A: Phys. 206: 57-66. (IF=1.841).
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Wong, S. T., Teo, S. K., Park, S., Chiam, K. H.* and Yim, E. K.* (2014). Anisotropic rigidity sensing on grating topography directs human mesenchymal stem cell elongation. Biomech Model Mechanobiol 13(1): 27-39. (IF=3.192)
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Nam, S. W., Qian, C., Kim, S. H., van Noort, D., Chiam, K. H.* and Park, S.* (2013). C. elegans sensing of and entrainment along obstacles require different neurons at different body locations. Sci Rep 3: 3247. (IF=5.078).
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Jin, Y., Kim, S. H., Kim, M. and Park, S.* (2013) Continuous production of immunoliposomes using a microvalve-controlled microfluidic device (μFD). B Kor Chem Soc 34:2921-2923. (IF=0.982).
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Youn, M., Lee, K. M., Kim, S. H., Lim, J., Yoon, J. W.* and Park, S.* (2013). Escherichia coli O157:H7 LPS O-side chains and pO157 are required for killing Caenorhabditis elegans. Biochem Biophys Res Commun 436(3): 388-393.
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Noh, J. Y., Kim, S., Hwang, I. H., Lee, G. Y., Kang, J., Kim, S. H., Min, J., Park, S., Kim, C.*, Kim, J.* (2013). Solvent-dependent selective fluorescence assay of aluminum and gallium ions using julolidine-based probe. Dyes Pigment 99: 1016-1021. (IF=3.532)
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Nam, S. W., Kim, S. H., Park, J. K. and Park, S.* (2013). Dielectrophoresis in a slanted microchannel for separation of microparticles and bacteria. J Nanosci Nanotechnol 13(12): 7993-7997. (IF=1.563)
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Shumi, W., Kim, S. H., Lim, J., Cho, K. S., Han, H. and Park, S.* (2013). Shear stress tolerance of Streptococcus mutans aggregates determined by microfluidic funnel device (muFFD). J Microbiol Methods 93(2): 85-89. (IF=2.086)
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Kwon, M. G., Kim, D. S., Lee, J. H., Park, S. R., Ahn, J., Kim, J. S., Ko, K., Park, S., Kang, Y. S., Choo, Y. K., Ko, K.* (2013). Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract. Entomol Res 43: 101-107. (IF=0.981)
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Kwon, M. J., Kim, Y., Choi, Y., Kim, S. H., Park, S., Han, I., Kang, D. H. and Oh, E. S.* (2013). The extracellular domain of syndecan-2 regulates the interaction of HCT116 human colon carcinoma cells with fibronectin. Biochem Biophys Res Commun 431(3): 415-420. (IF=2.484)
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Cui, Y., Kim, S. H., Kim, H., Yeom, J., Ko, K., Park, W. and Park, S.* (2012). AFM probing the mechanism of synergistic effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) with cefotaxime against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. PLoS One 7(11): e48880.
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Oh, Y. J., Cui, Y., Kim, H., Li, Y., Hinterdorfer, P.* and Park, S.* (2012). Characterization of curli A production on living bacterial surfaces by scanning probe microscopy. Biophys J 103(8): 1666-1671. (IF=3.653)
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Shim, W., Paik, M. J., Nguyen, D. T., Lee, J. K., Lee, Y., Kim, J. H., Shin, E. H., Kang, J. S., Jung, H. S., Choi, S., Park, S., Shim, J. S. and Lee, G.* (2012). Analysis of changes in gene expression and metabolic profiles induced by silica-coated magnetic nanoparticles. ACS Nano 6(9): 7665-7680. (IF=11.421)
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Guo, Z., Nam, S. W., Park, S.*, Yoon, J.* (2012). A highly selective ratiometric near-infrared fluorescent cyanine sensor for cysteine with remarkable shift and its application bioimaging. Chem Sci 3:2760-2765. (IF=8.314)
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Kim, S., Noh, J. Y., Kim, K. Y., Kim, J. H., Kang, H. K., Nam, S. W., Kim, S. H., Park, S.*, Kim, C.* and Kim, J.* (2012). Salicylimine-based fluorescent chemosensor for aluminum ions and application to bioimaging. Inorg Chem 51(6): 3597-3602. (IF=4.601)
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Jeon, H., Lee, S., Li, Y., Park, S., Yoon, J.* (2012). Conjugated polydiacetylenes bearing quaternary ammonium groups as a dual colorimetric and fluorescent sensor for ATP. J Mater Chem A 22: 3795-3799. (IF=5.968)
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Wang, F., Nam, S. W., Guo, Z., Park, S.*, Yoon, J.* (2012). A new rhodamine derivative bearing benzothiazole and thiocarbonyl moieties as a highly selective fluorescent and colorimetric chemodosimeter for Hg2+ Sens. Actuator- B: Chem 161, 948-952. (IF=3.898)
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Cui, Y., Oh, Y. J., Lim, J., Youn, M., Lee, I., Pak, H. K., Park, W., Jo, W. and Park, S.* (2012). AFM study of the differential inhibitory effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against Gram-positive and Gram-negative bacteria. Food Microbiol 29(1): 80-87. (IF=3.283)
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Lee, H., Choi, M. K., Lee, D., Kim, H. S., Hwang, H., Kim, H., Park, S., Paik, Y. K. and Lee, J.* (2012). Nictation, a dispersal behavior of the nematode Caenorhabditis elegans, is regulated by IL2 neurons. Nat Neurosci 15(1): 107-112. (IF=15.531)
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Kim, J., Jang, Y., Byun, D.*, Kim, M., Nam, S. W., Park, S. (2011). Quantitative measurement of dynamic flow induced by Tetrahymena pyriformis (T. pyriformis) using micro-particle image velocimetry. J Visual-Japan 14: 361-370. (IF=0.435)
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Lim, J., Cui, Y., Oh, Y. J., Park, J. R., Jo, W., Cho, Y. H. and Park, S.* (2011). Studying the effect of alginate overproduction on Pseudomonas aeruginosa biofilm by atomic force microscopy. J Nanosci Nanotechnol 11(7): 5676-5681. (IF=1.563)
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Choi, J., Kim, S., Jung, J., Lim, Y., Kang, K., Park, S.* and Kang, S.* (2011). Wnt5a-mediating neurogenesis of human adipose tissue-derived stem cells in a 3D microfluidic cell culture system. Biomaterials 32(29): 7013-7022.(IF=7.404)
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Lim, J., Lee, K. M., Kim, S. H., Kim, Y., Kim, S. H., Park, W. and Park, S.* (2011). YkgM and ZinT proteins are required for maintaining intracellular zinc concentration and producing curli in enterohemorrhagic Escherichia coli (EHEC) O157:H7 under zinc deficient conditions. Int J Food Microbiol 149(2): 159-170.(IF=3.327)
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Lee, K. M., Lim, J., Nam, S., Yoon, M. Y., Kwon, Y. K., Jung, B. Y., Park, Y., Park, S. and Yoon, S. S.* (2011). Inhibitory effects of broccoli extract on Escherichia coli O157:H7 quorum sensing and in vivo virulence. FEMS Microbiol Lett 321(1): 67-74. (IF=2.044)
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Nam, S. W., Chen, X., Lim, J., Kim, S. H., Kim, S. T., Cho, Y. H., Yoon, J.* and Park, S.* (2011). In vivo fluorescence imaging of bacteriogenic cyanide in the lungs of live mice infected with cystic fibrosis pathogens. PLoS One 6(7): e21387. (IF=4.092)
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Kim, D., Park, S., Mahadevan, L. and Shin, J. H.* (2011). The shallow turn of a worm. J Exp Biol 214(Pt 9): 1554-1559. (IF=2.996)
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Lone, S., Kim, S. H.*, Nam, S. W., Park, S., Joo, J. and Cheong, I. W.* (2011). Microfluidic synthesis of Janus particles by UV-directed phase separation. Chem Commun (Camb) 47(9): 2634-2636. (IF=6.169)
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Kim, H. N., Nam, S. W., Swamy, K. M., Jin, Y., Chen, X., Kim, Y., Kim, S. J., Park, S.* and Yoon, J.* (2011). Rhodamine hydrazone derivatives as Hg2+ selective fluorescent and colorimetric chemosensors and their applications to bioimaging and microfluidic system. Analyst 136(7): 1339-1343. (Front Cover) (IF=4.230)
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Kim, S. H., Cui, Y., Lee, M. J., Nam, S. W., Oh, D., Kang, S. H., Kim, Y. S.* and Park, S.* (2011). Simple fabrication of hydrophilic nanochannels using the chemical bonding between activated ultrathin PDMS layer and cover glass by oxygen plasma. Lab Chip 11(2): 348-353. (IF=5.67)
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Shumi, W., Lim, J., Nam, S. W., Lee, K., Kim, S. H., Cho, K. S. and Park, S.* (2010). Environment factors affecting Streptococcus mutans biofilm formation in microfluidic device mimicking the teeth. BioChip J 4: 257-263. (IF=0.860)
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Chen, X., Nam, S. W., Kim, G. H., Song, N., Jeong, Y., Shin, I., Kim, S. K., Kim, J., Park, S.* and Yoon, J.* (2010). A near-infrared fluorescent sensor for detection of cyanide in aqueous solution and its application for bioimaging. Chem Commun (Camb) 46(47): 8953-8955. (IF=6.169)
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Lone, S., Kim, S. H.*, Nam, S. W., Park, S. and Cheong, I. W.* (2010). Microfluidic preparation of dual stimuli-responsive microparticles and light-directed clustering. Langmuir 26(23): 17975-17980. (IF=4.186)
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Xu, Z., Singh, N. J., Lim, J., Pan, J., Kim, H. N., Park, S., Kim, K. S.* and Yoon, J.* (2009). Unique sandwich stacking of pyrene-adenine-pyrene for selective and ratiometric fluorescent sensing of ATP at physiological pH. J Am Chem Soc 131(42): 15528-15533. (IF=9.907)
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Kou, S., Nam, S.-W., Shumi, W., Lee, M. H., Bae, S. W., Du, J., Kim, J. S., Hong, J.-I., Peng, X., Yoon, J.* and Park , S.* (2009). Microfluidic detection of multiple heavy metal ions using fluorescent chemosensors. B Kor Chem Soc 30:1173-1176. (IF=0.906)
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Shumi, W., Lim, J., Nam, S. W., Kim, S. H., Cho, K. S., Yoon, J. and Park, S.* (2009). Fluorescence imaging of the spatial distribution of ferric ions over biofilms formed by Streptococcus mutans under microfluidic conditions. BioChip J 3: 119-124. (IF=0.860)
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Nam, S. W., Kim, S. T., Lee, K. M., Kim, S. H., Kou, S., Lim, J., Hwang, H., Joo, M. K., Jeong, B., Yoo, S. H. and Park, S.* (2009). N-Methyl-D-aspartate receptor-mediated chemotaxis and Ca(2+) signaling in Tetrahymena pyriformis. Protist 160(2): 331-342. (IF=3.136)
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Chen, X., Jou, M. J., Lee, H., Kou, S., Lim, J., Nam, S. W., Park, S.*, Kim, K. M.* and Yoon, J.* (2009). New fluorescent and colorimetric chemosensors bearing rhodamine and binaphthyl groups for the detection of Cu2+. Sensor Actuat B-Chem 137: 597-602. (IF=3.898)
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Kim, Y., Oh, S., Park, S., and Kim, S. H.* (2009). Transcriptome analysis for interaction between enterohemorrahgic Escherichia coli (EHEC) O157:H7 attachment and intestinal epithelial HT-29 Cells. Int J Food Microbiol, 131: 224-232. (IF=3.327)
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Chung, S. Y., Nam, S. W., Lim, J., Park, S.* and Yoon, J.* (2009). A highly selective cyanide sensing in water via fluorescence change and its application to in vivo imaging. Chem Commun (Camb)(20): 2866-2868. (IF=6.169)
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Nam, S., Min, K., Hwang, H., Lee, H. O., Lee, J. H., Yoon, J., Lee, H., Park, S. and Lee, J.* (2009). Control of rapsyn stability by the CUL-3-containing E3 ligase complex. J Biol Chem 284(12): 8195-8206. (IF=4.773)
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Lee, K. M., Kim, W. S., Lim, J., Nam, S., Youn, M., Nam, S. W., Kim, Y., Kim, S. H., Park, W. and Park, S.* (2009). Antipathogenic properties of green tea polyphenol epigallocatechin gallate at concentrations below the MIC against enterohemorrhagic Escherichia coli O157:H7. J Food Prot 72(2): 325-331. (IF=1.937)
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Lim, J. S., Lee, K. M., Kim, S. H., Nam, S. W., Oh, Y. J., Yun, H. S., Jo, W., Oh, S., Kim, S. and Park, S.* (2008). Nanoscale characterization of Escherichia coli biofilm formed under laminar flow using atomic force microscopy (AFM) and scanning electron microscopy (SEM). B Kor Chem Soc 29: 2114-2118. (IF=0.906)
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Choi, W., Nam, S. W., Hwang, H., Park, S.* and Park, J.* (2008). Programmable manipulation of motile cells in optoelectronic tweezers using a grayscale image. Appl Phys Lett 93: 143901-143903. (IF=3.844)
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Chen, X., Nam, S. W., Jou, M. J., Kim, Y., Kim, S. J., Park, S.* and Yoon, J.* (2008). Hg2+ selective fluorescent and colorimetric sensor: its crystal structure and application to bioimaging. Org Lett 10(22): 5235-5238. (IF=5.862)
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Oh, Y. J., Jo, W.*, Kim, S., Park, S. and Kim, Y. S. (2008). Nanoscale observation of local bound charges of patterned protein arrays by scanning force microscopy. Nanotechnology 19(36): 365302-365306. (IF=3.979)
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Galajda, P., Keymer, J., Dalland, J., Park, S., Kou, S. and Austin, R.* (2008). Funnel ratchets in biology at low Reynolds number: choanotaxis. J Mod Optic 155: 3413-3422. (IF=1.170)
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Park, S., Hwang, H., Nam, S. W., Martinez, F., Austin, R. H. and Ryu, W. S.* (2008). Enhanced Caenorhabditis elegans locomotion in a structured microfluidic environment. PLoS One 3(6): e2550. (IF=4.092)
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Kwon, S. K., Kou, S., Kim, H. N., Chen, X., Hwang, H., Nam, S. W., Kim, S. H., , Swamy, K. M. K.*, Park, S. * and Yoon, J.* (2008) Sensing cyanide ion via fluorescent change and its application to the microfluidic system. Tetrahedron Lett 49:4102-4105. (IF=2.683)
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Yang, Y., Nam, S. W., Lee, N. Y., Kim, Y. S. and Park, S.* (2008). Superporous agarose beads as a solid support for microfluidic immunoassay. Ultramicroscopy 108(10): 1384-1389. (IF=2.471)
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Oh, Y. J., Jo, W.*, Lim, J., Park, S., Kim, Y. S. and Kim, Y. (2008). Micropatterning of bacteria on two-dimensional lattice protein surface observed by atomic force microscopy. Ultramicroscopy 108(10): 1124-1127. (IF=2.471)
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Ong, S. M., Zhang, C., Toh, Y. C., Kim, S. H., Foo, H. L., Tan, C. H., van Noort, D., Park, S. and Yu, H. (2008). A gel-free 3D microfluidic cell culture system. Biomaterials 29(22): 3237-3244. (IF=7.404)
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Kim, J. A., Hwang, H., Jun, E. J., , Nam, S. W., Lee, K. M., Kim, S. H., Yoon, J., Kang, S., Park, S.* (2008). A microfluidic platform for preconcentrating and detecting Cu(II) with a fluorescent chemosensor and Cu(II)-Chelating alginate beads. B Korn Chem Soc 29: 225-227. (IF=0.906)
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Lee, Y., Kim, Y., Yeom, S., Kim, S., Park, S., Jeon, C. O. and Park, W. (2008). The role of disulfide bond isomerase A (DsbA) of Escherichia coli O157:H7 in biofilm formation and virulence. FEMS Microbiol Lett 278(2): 213-222. (IF=2.044)
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Lee, H. N., Kim, H. N., Swamy, K. M. K., Park, M. S., Kim, J., Lee, H., Lee, K. H., Park, S., Yoon, J.* (2008). New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+. Tetrahedron Lett 49: 1261-1265. (IF=2.683)
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Kim, Y., Oh, S., Park, S., Seo, J. B., Kim, S.* (2008). Lactobacillus acidophilus reduces expression of enterohemorrhagic Escherichia coli O157:H7 virulence factors by inhibiting autoinducer-2-like activity. Food Control 19:1042-1050. (IF=2.656)
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Kou, S., Lee, H. N., van Noort, D., Swamy, K. M., Kim, S. H., Soh, J. H., Lee, K. M., Nam, S. W., Yoon, J.* and Park, S.* (2008). Fluorescent molecular logic gates using microfluidic devices. Angew Chem Int Ed Engl 47(5): 872-876. (Inside cover) (IF=13.455)
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Kim, S. H., Yang, Y., Kim, M., Nam, S. W., Lee, K. M., Lee, N. Y. and Kim, Y.S.* and Park, S.* (2007) A simple route to hydrophilic microfluidic chip fabrication with ultraviolet ray (UV)-cured polymer. Adv Funct Mater 17: 3493-3498. (IF=10.179)
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Oh, Y. J., Jo, W.*, Yang, Y. and Park, S.* (2007). Influence of culture conditions on Escherichia coli O157:H7 biofilm formation by atomic force microscopy. Ultramicroscopy 107(10-11): 869-874. (IF=2.471)
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Nam, S. W., Van Noort, D., Yang, Y. and Park, S. (2007). A biological sensor platform using a pneumatic-valve controlled microfluidic device containing Tetrahymena pyriformis. Lab Chip 7(5): 638-640. (IF=5.67)
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Kim, Y., Oh, S., Ahn, E. Y., Imm, J. Y., Oh, S., Park, S. and Kim, S. H.* (2007). Proteome analysis of virulence factor regulated by autoinducer-2-like activity in Escherichia coli O157:H7. J Food Prot 70(2): 300-307. (IF=1.937)
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Oh, Y. J., Yang, Y., Park, S. and Jo, W. * (2007) Biofilm formation and local electrostatic force characteristics of Escherichia coli O157:H7 observed by electrostatic force microscopy. Appl Phys Lett 90: 143901-143903. (IF=3.844)
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Kim, Y. H., Lee, Y., Kim, S., Yeom, J., Yeom, S., Seok Kim, B., Oh, S., Park, S., Jeon, C. O. and Park, W.* (2006). The role of periplasmic antioxidant enzymes (superoxide dismutase and thiol peroxidase) of the Shiga toxin-producing Escherichia coli O157:H7 in the formation of biofilms. Proteomics 6(23): 6181-6193. (IF=4.505)
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Kim, Y., Han, K. S., Imm, J. Y., Oh, S., You, S., Park, S. and Kim, S. H.* (2006). Inhibitory effects of Lactobacillus acidophilus lysates on the cytotoxic activity of shiga-like toxin 2 produced from Escherichia coli O157:H7. Lett Appl Microbiol 43(5): 502-507. (IF=1.622)
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Keymer, J. E., Galajda, P., Muldoon, C., Park, S. and Austin, R. H.* (2006). Bacterial metapopulations in nanofabricated landscapes. Proc Natl Acad Sci U S A 103(46): 17290-17295. (Cover) (Selected by Faculty of 1000) (IF=9.681)
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Lee, N. Y., Lim, J. R., Lee, M. J., Park, S. and Kim, Y. S.* (2006). Multilayer transfer printing on microreservoir-patterned substrate employing hydrophilic composite mold for selective immobilization of biomolecules. Langmuir 22(18): 7689-7694. (IF=4.186)
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Son, H., Lim, Y., Kim, J., Park, H., Choi, S., Han, I., Kim, W. S., Park, S., Bae, Y. and Oh, E. S.* (2006). Protein kinase Calpha can undergo membrane localization via an alternative phosphatidylinositol 4,5-bisphosphate-dependent pathway. Arch Biochem Biophys 454(1): 1-6. (IF=2.935)
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Oh, Y. J., Kim, J. A., Park, S. and Jo, W.* (2006) Immobilization and observation of particles with 3-aminopropyltrimethoxysilane studied by scanning probe microscopy. J Kor Phys Soc 48: 1642-1645. (IF=0.447)
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Lee, N. Y., Yang, Y., Kim, Y. S. and Park, S.* (2006) Microfluidic immunoassay platform using antibody-immobilized glass beads and its application for detection of Escherichia coli O157:H7. B Kor Chem Soc 27:479-483. (IF=0.906)
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Oh, S., Kim, S. H., Ko, Y., Sim, J. H., Kim, K. S., Lee, S. H., Park, S. and Kim, Y. J.* (2006). Effect of bacteriocin produced by Lactococcus sp. HY 449 on skin-inflammatory bacteria. Food Chem Toxicol 44(4): 552-559. (IF=2.999)
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Lee, Y., Jung, E., Ahn, E., Park, S., Madsen, E. L., Jeon, C. O. and Park, W.* (2006) Construction of a reporter strain Pseudomonas putida for the detection of oxidative stress caused by environmental pollutants. World J Microb Biot 16: 386-390. (IF=1.381)
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Jun, E. J., Kim, J. A., Swamy, K. M. K., Park, S.* and Yoon, J.* (2006) A fluorescein derivative for nanomolar aqueous copper and monitoring copper ion uptake by transferrin and amyloid precursor protein. Tetrahedron Lett 47:1051-1054. (IF=2.683)
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Lee, M. J., Lee, N. Y., Lee, S. K., Park, S. and Kim, Y. S.* (2005) Polyelectrolyte micropatterning using agarose plane stamp and a substrate having microscale features on its surface. B Kor Chem Soc 26:1539-1542. (IF=0.906)
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Kim, Y. S.*, Lee, N. Y., Lim, J. R., Lee, M. J. and Park, S. (2005) Nanofeature-patterned polymer mold fabrication toward precisely defined nanostructure replication. Chem Mater 17: 5867-5870. (IF=7.286)
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Han, K. S., Kim, Y., Choi, S., Oh, S., Park, S., Kim, S. H.* and Whang, K. Y. (2005). Rapid identification of Lactobacillus acidophilus by restriction analysis of the 16S-23S rRNA intergenic spacer region and flanking 23S rRNA gene. Biotechnol Lett 27(16): 1183-1188. (IF=1.683)