Education
Ph.D., University of Aix-Marseille II, Marseille, France, 2008
Current position
Research Scientist, Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia
Publications
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Benoit, M. E., Clarke, E. V. and Tenner, A. J. (2013). C1q binding to and uptake of apoptotic lymphocytes by human monocyte-derived macrophages. Bio-protocol, 3(17):http://www.bio-protocol.org/wenzhang.aspx?id=877.
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Benoit, M. E., Hernandez, M. X., Dinh, M. L., Benavente, F., Vasquez, O. and Tenner, A. J. (2013). C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity. J Biol Chem 288(1): 654-665.
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Benoit, M. E., Clarke, E. V., Morgado, P., Fraser, D. A. and Tenner, A. J. (2012). Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells. J Immunol 188(11): 5682-5693.
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Benoit, M. E. and Tenner, A. J. (2011). Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression. J Neurosci 31(9): 3459-3469.
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Fonseca, M. I., Chu, S. H., Berci, A. M., Benoit, M. E., Peters, D. G., Kimura, Y. and Tenner, A. J. (2011). Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. J Neuroinflammation 8(1): 4.
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Benoit, M., Thuny, F., Le Priol, Y., Lepidi, H., Bastonero, S., Casalta, J. P., Collart, F., Capo, C., Raoult, D. and Mege, J. L. (2010). The transcriptional programme of human heart valves reveals the natural history of infective endocarditis. PLoS One 5(1): e8939.
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Benoit, M., Bechah, Y., Capo, C., Murray, P. J., Mege, J. L. and Desnues, B. (2009). Role of the cytoplasmic pattern recognition receptor Nod2 in Coxiella burnetii infection. Clin Microbiol Infect 15 Suppl 2: 154-155.
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Benoit, M., Desnues, B. and Mege, J. L. (2008). Macrophage polarization in bacterial infections. J Immunol 181(6): 3733-3739. Review.
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Benoit, M., Ghigo, E., Capo, C., Raoult, D. and Mege, J. L. (2008). The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis. PLoS Pathog 4(5): e1000066.
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Benoit, M., Barbarat, B., Bernard, A., Olive, D. and Mege, J. L. (2008). Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages. Eur J Immunol 38(4): 1065-1070.
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Benoit, M., Fenollar, F., Raoult, D. and Mege, J. L. (2007). Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease. PLoS One 2(6): e494.