教育背景
PhD, University of California, Davis, 2021
实验室信息
I'm currently a Scientist, Applied Bioinformatics focusing on single cell sequencing bioinformatics analysis. I finished my PhD degree at University of California, Davis at Dr. Janine LaSalle's lab, where I identified epigenetics targeted regions associated with Autism Spectrum Disorder (ASD) as biomarker for early detection using whole genome bisulfite sequencing, whole genome sequencing and EPIC-array.
https://mmi-lab.ucdavis.edu/
研究方向
epigenetics, single cell, bioinformatics
发表论文
https://scholar.google.com/citations?user=ZyzC7KYAAAAJ&hl=enZhu, Y., et al. (2022) Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Revision at Genome Biology.
Zhu, Y., et al. (2020) Expression changes in immune and epigenetic gene pathways associated with nutritional metabolites in maternal blood from pregnancies resulting in autism. Autism Research.
Mordaunt, C.E., …, Zhu, Y., …, LaSalle, J.M. (2020) Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes. Genome Medicine.
Sun, C., …, Zhu, Y., ..., Vicario, S. (2020) Genus-wide characterization of bumblebee genomes reveals variation associated with key ecological and behavioral traits of pollinators. Molecular Biology and Evolution.
Zhu, Y., et al. (2019). Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. Human molecular genetics.
Mordaunt, C. E., ..., Zhu, Y., …, Medici, V. (2019). Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers. Epigenetics & Chromatin.
Coulson, R.L., …, Zhu, Y., ..., LaSalle, J.M. (2018). Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. Nature communications.