1. Barnes GL, Magann NL, Perrotta D, Hörmann FM, Fernandez S, Vydyam P, Choi JY, Prudhomme J, Neal A, Le Roch KG, Ben Mamoun C, Vanderwal CD. A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents. J Am Chem Soc. 2024 Oct 30;146(43):29883-29894. doi: 10.1021/jacs.4c11897. Epub 2024 Oct 16. PMID: 39412402; PMCID: PMC11528414.
2. Singh P, Vydyam P, Fang T, Estrada K, Gonzalez LM, Grande R, Kumar M, Chakravarty S, Berry V, Ranwez V, Carcy B, Depoix D, Sánchez S, Cornillot E, Abel S, Ciampossin L, Lenz T, Harb O, Sanchez-Flores A, Montero E, Le Roch KG, Lonardi S, Mamoun CB. Insights into the evolution, virulence and speciation of Babesia MO1 and Babesia divergens through multiomics analyses. Emerg Microbes Infect. 2024 Dec;13(1):2386136. doi: 10.1080/22221751.2024.2386136. Epub 2024 Sep 1. PMID: 39148308; PMCID: PMC11370697.
3. Chahine Z, Abel S, Hollin T, Barnes GL, Chung JH, Daub ME, Renard I, Choi JY, Vydyam P, Pal A, Alba-Argomaniz M, Banks CAS, Kirkwood J, Saraf A, Camino I, Castaneda P, Cuevas MC, De Mercado-Arnanz J, Fernandez-Alvaro E, Garcia-Perez A, Ibarz N, Viera-Morilla S, Prudhomme J, Joyner CJ, Bei AK, Florens L, Ben Mamoun C, Vanderwal CD, Le Roch KG. A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science. 2024 Sep 27;385(6716):eadm7966. doi: 10.1126/science.adm7966. Epub 2024 Sep 27. PMID: 39325875.
4. Vydyam P, Chand M, Gihaz S, Renard I, Heffernan GD, Jacobus LR, Jacobus DP, Saionz KW, Shah R, Shieh H-M, Terpinski J, Zhao W, Cornillot E, Ben Mamoun C. In vitro efficacy of next-generation dihydrotriazines and biguanides against babesiosis and malaria parasites. Antimicrob Agents Chemother. 2024 Aug 13:e0042324. doi: 10.1128/aac.00423-24
5. Chand M, Vydyam P, Pal AC, Thekkiniath J, Darif D, Li Z, Choi JY, Magni R, Luchini A, Tonnetti L, Horn EJ, Tufts DM, Ben Mamoun C. A set of diagnostic tests for detection of active Babesia duncani infection. Int J Infect Dis. 2024 Jul 25;147:107178. doi: 10.1016/j.ijid.2024.107178. PMID: 39025200.
6. Choi JY, Gihaz S, Munshi M, Singh P, Vydyam P, Hamel P, Adams EM, Sun X, Khalimonchuk O, Fuller K, Ben Mamoun C. Vitamin B5 metabolism is essential for vacuolar and mitochondrial functions and drug detoxification in fungi. Commun Biol. 2024 Jul 23;7(1):894. doi: 10.1038/s42003-024-06595-7. PMID: 39043829; PMCID: PMC11266677.
7. Vydyam P., Chand, M., Pou, S., Winter, R. W., Liebman, K. M., Nilsen, A., Doggett, J. S., Riscoe, M. K., & Ben Mamoun, C. (2024). Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS infectious diseases, 10(4), 1405–1413.
8. Ben Mamoun, C., & Vydyam, P. (2024). Response to the Letter by Liu and Colleagues. The Journal of infectious diseases, 229(5), 1601. https://doi.org/10.1093/infdis/jiae084
9. Vydyam P, Pal AC, Renard I, Chand M, Kumari V, Gennaro JC, Mamoun CB. Tafenoquine-Atovaquone Combination Achieves Radical Cure and Confers Sterile Immunity in Experimental Models of Human Babesiosis. J Infect Dis. 2024 Jan 12;229(1):161-172. doi: 10.1093/infdis/jiad315. PMID: 38169301; PMCID: PMC10786256.
10. Vydyam P, Choi JY, Gihaz S, Chand M, Gewirtz M, Thekkiniath J, Lonardi S, Gennaro JC, Ben Mamoun C. Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril. J Biol Chem. 2023 Nov;299(11):105313. doi: 10.1016/j.jbc.2023.105313. Epub 2023 Oct 4. PMID: 37797695; PMCID: PMC10663679.
11. Vydyam P, Roy N, Bhattacharyya MK. Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum. Front Mol Biosci. 2023 Aug 1;10:1223682. doi: 10.3389/fmolb.2023.1223682. PMID: 37593128; PMCID: PMC10427863.
12. Singh P, Lonardi S, Liang Q, Vydyam P, Khabirova E, Fang T, Gihaz S, Thekkiniath J, Munshi M, Abel S, Ciampossin L, Batugedara G, Gupta M, Lu XM, Lenz T, Chakravarty S, Cornillot E, Hu Y, Ma W, Gonzalez LM, Sánchez S, Estrada K, Sánchez-Flores A, Montero E, Harb OS, Le Roch KG, Mamoun CB. Babesia duncani multi-omics identifies virulence factors and drug targets. Nat Microbiol. 2023 May;8(5):845-859. doi: 10.1038/s41564-023-01360-8. Epub 2023 Apr 13. PMID: 37055610; PMCID: PMC10159843.
13. Mannuthodikayil J, Sinha S, Singh S, Biswas A, Ali I, Mashurabad PC, Tabassum W, Vydyam P, Bhattacharyya MK, Mandal K. A Chimeric Peptide Inhibits Red Blood Cell Invasion by Plasmodium falciparum with Hundredfold Increased Efficacy. Chembiochem. 2023 Apr 3;24(7):e202200533. doi: 10.1002/cbic.202200533. Epub 2022 Dec 23. PMID: 36449557.
14. Pal AC, Renard I, Singh P, Vydyam P, Chiu JE, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Ben Mamoun C. Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo. J Infect Dis. 2022 Sep 28;226(7):1267-1275. doi: 10.1093/infdis/jiac181. PMID: 35512141; PMCID: PMC10233494.
15. George S, Pal AC, Gagnon J, Timalsina S, Singh P, Vydyam P, Munshi M, Chiu JE, Renard I, Harden CA, Ott IM, Watkins AE, Vogels CBF, Lu P, Tokuyama M, Venkataraman A, Casanovas-Massana A, Wyllie AL, Rao V, Campbell M, Farhadian SF, Grubaugh ND, Dela Cruz CS, Ko AI, Berna Perez AZ, Akaho EH, Moledina DG, Testani J, John AR, Ledizet M, Mamoun CB; and the Yale IMPACT Team. Evidence for SARS-CoV-2 Spike Protein in the Urine of COVID-19 Patients. Kidney360. 2021 Apr 14;2(6):924-936. doi: 10.34067/KID.0002172021. PMID: 35373072; PMCID: PMC8791366.
16. Chiu JE, Renard I, Pal AC, Singh P, Vydyam P, Thekkiniath J, Kumar M, Gihaz S, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Mamoun CB. Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0066221. doi: 10.1128/AAC.00662-21. Epub 2021 Aug 17. PMID: 34152821; PMCID: PMC8370247.
17. Mannuthodikayil J, Singh S, Biswas A, Kar A, Tabassum W, Vydyam P, Bhattacharyya MK, Mandal K. Benzimidazolinone-Free Peptide o-Aminoanilides for Chemical Protein Synthesis. Org Lett. 2019 Nov 15;21(22):9040-9044. doi: 10.1021/acs.orglett.9b03440. Epub 2019 Oct 30. PMID: 31663760.
18. Vydyam P, Dutta D, Sutram N, Bhattacharyya S, Bhattacharyya MK. A small-molecule inhibitor of the DNA recombinase Rad51 from Plasmodium falciparum synergizes with the antimalarial drugs artemisinin and chloroquine. J Biol Chem. 2019 May 17;294(20):8171-8183. doi: 10.1074/jbc.RA118.005009. Epub 2019 Apr 1. PMID: 30936202; PMCID: PMC6527153.
19. Badugu SB, Nabi SA, Vydyam P, Laskar S, Bhattacharyya S, Bhattacharyya MK. Correction: Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function. PLoS One. 2023 Oct 31;18(10):e0293936. doi: 10.1371/journal.pone.0293936. Erratum for: PLoS One. 2015 May 04;10(5):e0125358. PMID: 37906581; PMCID: PMC10617721.