Journal Articles: (*corresponding author)
1. Chih-Tien Wang, Ruey-Ling Huang, Mei-Yun Tai, Yuan-Feen Tsai and Ming-Tsung Peng. Dopamine release in the nucleus accumbens during sexual behavior in prenatally stressed adult male rats. Neuroscience Letters. 1995 Nov 10; 200(1): 29-32.
2. Ruey-Ling Huang, Chih-Tien Wang, Mei-Yun Tai, Yuan-Feen Tsai and Ming-Tsung Peng. Effects of age on dopamine release in the nucleus accumbens and amphetamine-induced locomotor activity in rats. Neuroscience Letters. 1995 Nov 10; 200(1): 61-4.
3. Chih-Tien Wang, Hai-Guang Zhang, Thomas A. Rocheleau, Richard H. ffrench-Constant and Meyer B. Jackson. Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila. Biophysical Journal. 1999 Aug; 77(2): 691-700.
4. Chih-Tien Wang, Rusland Grishanin, Cynthia A. Earles, Payne Y. Chang, Thomas F. J. Martin, Edwin R. Chapman and Meyer B. Jackson. Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles. Science. 2001 Nov 2; 294(5544): 1111-5.
5. J. Michael Edwardson, Chih-Tien Wang, Belvin Gong, Andreas Wyttenbach, Jihong Bai, Meyer B. Jackson, Edwin R. Chapman and A. Jennifer Morton. Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II. Journal of Biological Chemistry. 2003 Aug 15; 278(33): 30849-53.
6. Chih-Tien Wang, Juu-Chin Lu, Jihong Bai, Payne Y. Chang, Thomas F. J. Martin, Edwin R. Chapman and Meyer B. Jackson. Different domains of synaptotagmin control the choice between kiss-and-run and full fusion. Nature. 2003 Aug 21; 424(6951): 943-7.
7. Ping Wang, Chih-Tien Wang, Jihong Bai, Meyer B. Jackson and Edwin R. Chapman. Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner. Journal of Biological Chemistry. 2003 Nov 21; 278(47): 47030-7.
8. Jihong Bai, Chih-Tien Wang, David A. Richards, Meyer B. Jackson and Edwin R. Chapman. Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions. Neuron. 2004 Mar 25; 41(6): 929-42.
9. Xue Han, Chih-Tien Wang, Jihong Bai, Edwin R. Chapman and Meyer B. Jackson. Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis. Science. 2004 Apr 9; 304(5668): 289-92.
10. Christine Torborg, Chih-Tien Wang, Gianna Muir-Robinson and Marla B. Feller. L-type calcium channel agonist induces correlated depolarizations in mice lacking the 2 subunit nAChRs. Vision Research. 2004 Dec; 44(28): 3347-55.
11. Sally I. Firth, Chih-Tien Wang and Marla B. Feller. Retinal waves: Mechanisms and function in visual system development. Cell Calcium. 2005 Apr 9; 37: 425-32.
12. Chih-Tien Wang, Jihong Bai, Payne Y. Chang, Edwin R. Chapman and Meyer B. Jackson. Synaptotagmin*calcium triggers two sequential steps in regulated exocytosis in rat PC12 cells: Fusion pore opening and fusion pore dilation. Journal of Physiology (London). 2006 Jan 15;570(Pt 2):295-307.
13. Chih-Tien Wang1, Hao-Ai Shui1, Ruey-Ling Huang, Mei-Yun Tai, Ming-Tsung Peng and Yuan-Feen Tsai. Sexual motivation is demasculinized, but not feminized, in prenatally stressed male rats. Neuroscience. 2006 Jan 4;138(2):357-64. (1These authors contributed equally to this work.)
14. Timothy A. Dunn1, Chih-Tien Wang1, Michael A. Colicos, Manuela Zaccolo, Lisa M. DePilato, Jin Zhang, Roger Y. Tsien and Marla B. Feller. Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drives oscillations in second- messenger cascade. The Journal of Neuroscience. 2006 Dec 6; 26(49): 12807-15. (1These two first authors contributed equally.)
15. Chih-Tien Wang, Aaron G. Blankenship, Anastasia Anishchenko, Justin Elstrott, Michael Fikhman, Shigetada Nakanishi and Marla B. Feller. GABAA receptor-mediated signaling alters the structure of spontaneous activity in the developing retina. The Journal of Neuroscience. 2007 Aug 22; 27(34): 9130-40.
16. Chung-Wei Chiang, Yu-Chieh Chen, Juu-Chin Lu, Yu-Tien Hsiao, Che-Wei Chang, Pin-Chien Huang, Yu-Tzu Chang, Payne Y. Chang and Chih-Tien Wang*. Synaptotagmin I regulates patterned spontaneous activity in the developing rat retina via calcium binding to the C2AB domains. PLoS One. 2012 Oct 16; 7(10): e47465.
17. Juu-Chin Lu, Yu-Tien Hsiao, Chung-Wei Chiang and Chih-Tien Wang*. GABAA receptor-mediated tonic depolarization in the developing neural circuits. Molecular Neurobiol. 2014 Apr 1; 49(2): 702-23.
18. Pin-Chien Huang, Yu-Tien Hsiao, Shao-Yen Kao, Ching-Feng Chen, Yu-Chieh Chen, Chung-Wei Chiang, Ching-fei Lee, Juu-Chin Lu, Yijuang Chern and Chih-Tien Wang*. Adenosine A2A receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina. PLoS One. 2014 Apr 28; 9(4): e95090.
19. Ning Chiang, Yu-Tien Hsiao, Hui-Ju Yang, Yu-Chun Lin, Juu-Chin Lu* and Chih-Tien Wang*. Phosphomimetic mutation of cysteine string protein- increases the rate of regulated exocytosis by modulating fusion pore dynamics in PC12 cells. PLoS One. 2014 Jun 23; 9(6): e99180.
20. Chi-Wei Zeng, Yosuhiro Kamei, Chih-Tien Wang, and Hui-Jen Tsai*. Subtypes of hypoxia‐responsive cells differentiate into neurons in spinal cord of zebrafish embryos after hypoxic stress. Biology of the Cell. 2016 Dec; 108(12):357-377.
21. Yu-Tien Hsiao, Wen-Chi Shu, Pin-Chun Chen, Hui-Ju Yang, Hsin-Yo Chen, Sheng-Ping Hsu, Yi-Ting Huang, Cheng-Chang Yang, Yen-Ju Chen, Ni-Yen Yu, Shih-Yuan Liou, Ning Chiang, Chien-Ting Huang Tzu-Lin Cheng, Lam-Yan Cheung, Yu-Chun Lin, Juu-Chin Lu*, and Chih-Tien Wang*. Presynaptic SNAP-25 regulates retinal waves and retinogeniculate projection via phosphorylation. Proc Natl Acad Sci U S A. 2019 Feb 19; 116(8):3262-3267.
22. Hui-Ju Yang, Pin-Chun Chen, Sheng-Ping Hsu, Chien-Ting Huang, Tzu-Lin Cheng, Chien-Yu Chen, Juu-Chin Lu*, and Chih-Tien Wang*. The synaptic vesicle-specific phosphoprotein Synapsin Ia regulates the kinetics of dense-core vesicle release. The Journal of Neuroscience. 2021 March 31; 41 (13): 2828-2841.
23. Ching-Feng Chen, Rita R. Wo, Chien-Ting Huang, Tzu-Lin Cheng, Juu-Chin Lu and Chih-Tien Wang*. Phosphorylation of cysteine string protein-α up-regulates the frequency of cholinergic waves via starburst amacrine cells. Visual Neuroscience. 2022 May 11; 39: E003.
24. Pin-Chun Chen and Chih-Tien Wang*. Rat Pheochromocytoma PC12 Cells in Culture. In: Borges, R. (eds) Chromaffin Cells. Methods in Molecular Biology. (ISBN: 978-1-0716-2671-9). New York, U.S.A. Humana Press. 2023 Jan 1; 2565: 3-15.
25. Yu-Tien Hsiao, Yu-Lin Su, Pin-Chun Chen, Chien-Ting Huang, Ya-Yun Hsieh, Ning Chiang, Yu-Chun Lin, Juu-Chin Lu* and Chih-Tien Wang*. Deficiency of PKA-mediated SNAP-25b phosphorylation destabilizes exocytotic fusion pores and reduces the interaction of t-SNAREs. The Journal of Physiology (London). 2025 October 15; 603(20):6073-6105. doi: 10.1113/JP286760.