发育生物学

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    现刊
    Lipid-exchange Rate Assay for Lipid Droplet Fusion in Live Cells
    活体细胞中脂滴融合的脂类交换速率检测
    作者:Jia Wang, Boon Tin Chua, Peng Li and Feng-Jung Chen日期:07/20/2019,浏览量:3853,Q&A: 0
    [Abstract] Lipid droplets (LDs) are central organelles in maintaining lipid homeostasis. Defective LD growth often results in the development of metabolic disorders. LD fusion and growth mediated by cell death–inducing DNA fragmentation factor alpha (DFFA)-like effector (CIDE) family proteins are crucial for various biological processes including unilocular ...
    In vivo Mitophagy Monitoring in Caenorhabditis elegans to Determine Mitochondrial Homeostasis
    秀丽隐杆线虫中的体内线粒体自噬监测以确定线粒体稳态
    作者:Konstantinos Palikaras and Nektarios Tavernarakis日期:04/05/2017,浏览量:8037,Q&A: 0
    [Abstract] Perturbation of mitochondrial function is a major hallmark of several pathological conditions and ageing, underlining the essential role of fine-tuned mitochondrial activity (Lopez-Otin et al., 2013). Mitochondrial selective autophagy, known as mitophagy, mediates the removal of dysfunctional and/or superfluous organelles, preserving ...