神经科学

分类

    现刊
    Low- and High-resolution Dynamic Analyses for Magnetic Resonance Spectroscopy Data
    磁共振光谱数据的低高分辨率动态分析
    作者:Reuben Rideaux日期:01/20/2021,浏览量:1466,Q&A: 0
    [Abstract]

    Magnetic resonance spectroscopy (MRS) can be used to measure in vivo concentrations of neurometabolites. This information can be used to identify neurotransmitter involvement in healthy (e.g., perceptual and cognitive processes) and unhealthy brain function (e.g., neurological and psychiatric illnesses). The standard approach for analyzing MRS

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    Precise Targeting of Single Microelectrodes to Orientation Pinwheel Centers
    单微电极精确定位风车中心区
    作者:Xue Mei Song, Ming Li, Tao Xu, Dewen Hu and Anna Wang Roe日期:06/05/2020,浏览量:1493,Q&A: 0
    [Abstract] In the mammalian visual system, early stages of visual form perception begin with orientation selective neurons in primary visual cortex (V1). In many species (including humans, monkeys, tree shrews, cats, and ferrets), these neurons are organized in pinwheel-like orientation columns. To study the functional organization within orientation ...
    Isoelectric Focusing to Quantify Rhodopsin Phosphorylation in Mouse Retina
    等电聚焦用于小鼠视网膜中磷酸化视紫红质的定量分析
    作者:Sowmya Bekshe Lokappa, M. Carter Cornwall and Jeannie Chen日期:07/20/2019,浏览量:4224,Q&A: 0
    [Abstract] Rhodopsin is a G-protein coupled receptor (GPCR) that mediates vision under dim light. Upon light exposure, rhodopsin is phosphorylated at multiple serine and threonine sites at its carboxyl-terminus by rhodopsin kinase (GRK1). This, in turn, reduces its ability to activate the visual G-protein transducin. Binding of light-activated, ...
    Embryonic Intravitreous Injection in Mouse
    小鼠胚胎期玻璃体腔注射
    作者:Liyuan Cui, Yupu Diao and Jiayi Zhang日期:07/20/2018,浏览量:3517,Q&A: 0
    [Abstract] Axons of retinal ganglion cells (RGCs) relay visual information from the retina to lateral geniculate nucleus (LGN) and superior colliculus (SC), which are two major image-forming visual nuclei. Wiring of these retinal projections completes before vision begins. However, there are few studies on retinal axons at embryonic stage due to technical ...
    Registration and Alignment Between in vivo Functional and Cytoarchitectonic Maps of Mouse Visual Cortex
    小鼠视皮层的体内功能和细胞结构图谱的配准和比对
    作者:Jun Zhuang, Quanxin Wang, Marc Takeno and Jack Waters日期:02/20/2018,浏览量:4266,Q&A: 0
    [Abstract] This protocol describes a method for registration of in vivo cortical retinotopic map with cytochrome c oxidase (CO) labeled architectonic maps of the same mouse brain through the alignment of vascular fiducials. By recording surface blood vessel pattern and sequential alignment at each step, this method overcomes the challenge imposed by ...