细胞生物学

分类

    现刊
    Muscle Cryoinjury and Quantification of Regenerating Myofibers in Mice
    小鼠肌肉低温损伤及再生肌纤维的定量研究
    作者:Yori Endo, Mehran Karvar and Indranil Sinha日期:06/05/2021,浏览量:1417,Q&A: 0
    [Abstract]

    Cryoinjury, or injury due to freezing, is a method of creating reproducible, local injuries in skeletal muscle. This method allows studying the regenerative response following muscle injuries in vivo, thus enabling the evaluation of local and systemic factors that influence the processes of myofiber regeneration. Cryoinjuries are applicable to the

    ...
    Wounding Caenorhabditis elegans with Glass Wool
    玻璃棉用于秀丽隐杆线虫的创伤研究
    作者:Murugesan Pooranachithra, James Prabhanand Bhaskar and Krishnaswamy Balamurugan日期:01/20/2021,浏览量:1365,Q&A: 0
    [Abstract]

    Research on wound healing majorly relies on rat, mice and other animal models. However, an alternative animal model ought to be brought in the field, pertaining to the stringent ethical issues owing to the use of animals in research. In this regard, Caenorhabdits elegans, a miniature model nematode gains the great attention of the researchers in

    ...
    Precision Technique for Splenectomy Limits Mouse Stress Responses for Accurate and Realistic Measurements for Investigating Inflammation and Immunity
    脾切除术限制小鼠应激反应的精准技术用于精确现实检测炎症和免疫
    作者:Shengwen Calvin Li, Anthony D. Rangel and Mustafa H. Kabeer日期:08/05/2019,浏览量:3143,Q&A: 0
    [Abstract] Splenectomy in an animal model requires a standardized technique utilizing best practice to avoid variability which can result in adverse impact to the animal resulting in flawed physiologic responses simply due to technique rather than to the studied variables. In the case of the spleen, often investigators are analyzing the animal immune or ...
    Morphological Evaluation of Wound Healing Events in the Excisional Wound Healing Model in Rats
    在大鼠切除创面愈合模型中进行伤口愈合的形态学评估
    [Abstract] Skin wound healing is a complex process involving different events such as blood coagulation, inflammation, new blood vessels formation, and extracellular matrix deposition. These events can be observed by using histology techniques. However, the lack of the standardization of such parameters impacts on the reproducibility of results. Here, we ...
    Partial Transection of Adult Rat Optic Nerve as a Model of Secondary Degeneration in the Central Nervous System
    成年大鼠视神经不完全横切作为中枢神经系统继发性损害模型
    作者:Carole A Bartlett and Melinda Fitzgerald日期:12/20/2018,浏览量:2890,Q&A: 0
    [Abstract] Injury to the central nervous system is characterized by damage that spreads from the initial point of impact into the surrounding adjacent tissue, in a phenomenon referred to as secondary degeneration. The optic nerve can be used to effectively model injury and secondary degeneration to white matter tracts. Partial transection of the dorsal ...
    Induction of Photothrombotic Stroke in the Sensorimotor Cortex of Rats and Preparation of Tissue for Analysis of Stroke Volume and Topographical Cortical Localization of Ischemic Infarct
    大鼠感觉运动皮层脑卒中的诱导性光栓疗法及用于卒中体积分析和缺血性梗死地形图皮层定位的组织制备
    作者:Anna M. Wiersma and Ian R. Winship日期:05/20/2018,浏览量:9198,Q&A: 0
    [Abstract] The photothrombotic model of stroke is commonly used in research as it allows the ischemic infarct to be targeted to specific regions of the cortex with high reproducibility and well-defined infarct borders. Unlike other models of stroke, photothrombosis allows the precise size and location of infarct to be tightly controlled with minimal surgical ...