分子生物学

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    现刊
    Affymetrix Genome-wide Human SNP Assay
    Affymetrix全基因组人单核苷酸多态性试验
    作者:Alexis Bosman日期:05/20/2016,浏览量:6665,Q&A: 0
    [Abstract] To assess genomic variation, it is possible to identify the single nucleotide polymorphisms (SNP) which an individual carries. Using the Affymetrix Genome-wide Human SNP Assay, it is possible to assess 906,600 SNPs on a single array. This protocol, the next iteration of the GeneChip Mapping 500K array set, is based directly on the manufacturers’ ...
    Gene Networks Based on the Graphical Gaussian Model
    高斯图模型构建基因网络
    作者:Shisong Ma日期:02/20/2012,浏览量:13298,Q&A: 1
    [Abstract] This protocol describes how to build a gene network based on the graphical Gaussian model (GGM) from large scale microarray data. GGM uses partial correlation coefficient (pcor) to infer co-expression relationship between genes. Compared to the traditional Pearson’ correlation coefficient, partial correlation is a better measurement of direct ...