癌症生物学

分类

    现刊
    Myeloid Progenitor Transformation Assay
    髓系祖细胞转化试验
    作者:Hiroshi Okuda and Akihiko Yokoyama日期:12/05/2017,浏览量:5689,Q&A: 0
    [Abstract] Numerous oncogenes have been identified to cause leukemia. For example, chromosomal translocation generates various fusion genes of the mixed-lineage leukemia (MLL) gene and a partner gene in leukemia, whose gene products transform primary myeloid progenitors into an immortalized state. To characterize the transforming ability of leukemic ...
    Isolation and Separation of Epithelial CD34+ Cancer Stem Cells from Tgfbr2-deficient Squamous Cell Carcinoma
    从Tgfbr2缺乏鳞状细胞癌分离上皮CD34+癌干细胞
    作者:Heather A. McCauley and Géraldine Guasch日期:09/05/2017,浏览量:6769,Q&A: 0
    [Abstract] Most epithelial tumors have been shown to contain cancer stem cells that are potentially the driving force in tumor progression and metastasis (Kreso and Dick, 2014; Nassar and Blanpain, 2016). To study these cells in depth, cell isolation strategies relying on cell surface markers or fluorescent reporters are essential, and the isolation ...
    In vitro and in vivo Limiting Dilution Assay for Colorectal Cancer
    结肠直肠癌的体外和体内限制稀释测定法
    作者:Lauren Agro and Catherine A O’Brien日期:11/20/2015,浏览量:20668,Q&A: 0
    [Abstract] The in vitro limiting dilution assay is used to determine the colorectal cancer initiating cell (CC-IC) frequency of a CC-IC enriched suspension culture, grown in growth factor enriched serum free media. The in vivo limiting dilution assay is used to determine the colorectal cancer initiating cell frequency of a primary ...