TT
Takemi Tanaka
  • Stephenson Cancer Center, University of Oklahoma Health Sciences Center, USA
研究方向
  • Cancer biology
个人信息

Current position

Associate Professor, University of Oklahoma, Stephenson Cancer Center, OK (2013-present)

Publications (since 2007)

  1. Kang, S. A., Hasan, N., Mann, A. P., Zheng, W., Zhao, L., Morris, L., Zhu, W., Zhao, Y. D., Suh, K. S., Dooley, W. C., Volk, D., Gorenstein, D. G., Cristofanilli, M., Rui, H. and Tanaka, T. (2015). Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis. Mol Ther 23(6): 1044-1054.
  2. Kang, S. A., Tsolmon, B., Mann, A. P., Zheng, W., Zhao, L., Zhao, Y. D., Volk, D. E., Lokesh, G. L., Morris, L., Gupta, V., Razaq, W., Rui, H., Suh, K. S., Gorenstein, D. G. and Tanaka, T. (2015). Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. Toxicol Appl Pharmacol 287(1): 86-92.
  3. Razak, W., Tanaka, T.and Razaq, M. (2015). Aromatase inhibitors and osteoporosis - risk, prevention and treatment. Journal of Osteoporosis and Physical Activity 3(3).
  4. Yang, N., Liu, C., Peck, A. R., Girondo, M. A., Yanac, A. F., Tran, T. H., Utama, F. E., Tanaka, T., Freydin, B., Chervoneva, I., Hyslop, T., Kovatich, A. J., Hooke, J. A., Shriver, C. D. and Rui, H. (2013). Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment. Breast Cancer Res 15(5): R73.
  5. Tamir, A., Jag, U., Sarojini, S., Schindewolf, C., Tanaka, T., Gharbaran, R., Patel, H., Sood, A., Hu, W., Patwa, R., Blake, P., Chirina, P., Oh Jeong, J., Lim, H., Goy, A., Pecora, A. and Suh, K. S. (2014). Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes. J Ovarian Res 7: 109.
  6. Gharbaran, R., Goy, A., Tanaka, T., Park, J., Kim, C., Hasan, N., Vemulapalli, S., Sarojini, S., Tuluc, M., Nalley, K., Bhattacharyya, P., Pecora, A. and Suh, K. S. (2013). Fibroblast growth factor-2 (FGF2) and syndecan-1 (SDC1) are potential biomarkers for putative circulating CD15+/CD30+ cells in poor outcome Hodgkin lymphoma patients. J Hematol Oncol 6: 62.
  7. Suh, K. S., Tanaka, T., Sarojini, S., Nightingale, G., Gharbaran, R., Pecora, A. and Goy, A. (2013). The role of the ubiquitin proteasome system in lymphoma. Crit Rev Oncol Hematol 87(3): 306-322.
  8. Mann, A. P. and Tanaka, T.* (2011). E-selectin: its role and potential as a biomarker. Translational Medicine S:1, http://dx.doi.org/10.4172/2161-1025.S1-002.
  9. Tanaka, T. and Suh, S. K. (2011). Nanomedicine in Cancer. Translational Medicine. http://dx.doi.org/10.4172/2161-1025.1000103e,1;1.
  10. Mann, A. P., Tanaka, T., Somasunderam, A., Liu, X., Gorenstein, D. G. and Ferrari, M. (2011). E-selectin-targeted porous silicon particle for nanoparticle delivery to the bone marrow. Adv Mater 23(36): H278-282.
  11. Mann, A. P., Tanaka, T., Somasunderam, A., Liu X., Gorenstein D. G. and Ferrari, M. (2011). Site-specific drug delivery. Advanced Material. 36 Cover.
  12. Mann, A. P., Bhavane, R. C., Somasunderam, A., Liz Montalvo-Ortiz, B., Ghaghada, K. B., Volk, D., Nieves-Alicea, R., Suh, K. S., Ferrari, M., Annapragada, A., Gorenstein, D. G. and Tanaka, T. (2011). Thioaptamer conjugated liposomes for tumor vasculature targeting. Oncotarget 2(4): 298-304.
  13. Serda, R. E., Blanco, E., Mack, A., Stafford, S. J., Amra, S., Li, Q., van de Ven, A., Tanaka, T., Torchilin, V. P., Wiktorowicz, J. E. and Ferrari, M. (2011). Proteomic analysis of serum opsonins impacting biodistribution and cellular association of porous silicon microparticles. Mol Imaging 10(1): 43-55.
  14. Mann, A. P., Somasunderam, A., Nieves-Alicea, R., Li, X., Hu, A., Sood, A. K., Ferrari, M., Gorenstein, D. G. and Tanaka, T.* (2010). Identification of thioaptamer ligand against E-selectin: potential application for inflamed vasculature targeting. PLoS One 5(9).
  15. Somasunderam, A., Thiviyanathan, V., Tanaka, T., Li, X., Neerathilingam, M., Lokesh, G. L., Mann, A., Peng, Y., Ferrari, M., Klostergaard, J. and Gorenstein, D. G. (2010). Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44. Biochemistry 49(42): 9106-9112.
  16. Guleria, R. S., Choudhary, R., Tanaka, T., Baker, K. M. and Pan, J. (2011). Retinoic acid receptor-mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: role of the renin-angiotensin system. J Cell Physiol 226(5): 1292-1307.
  17. Tanaka, T., Godin, B., Bhavane, R., Nieves-Alicea, R., Gu, J., Liu, X., Chiappini, C., Fakhoury, J. R., Amra, S., Ewing, A., Li, Q., Fidler, I. J. and Ferrari, M. (2010). In vivo evaluation of safety of nanoporous silicon carriers following single and multiple dose intravenous administrations in mice. Int J Pharm 402(1-2): 190-197.
  18. Godin, B., Gu, J., Serda, R. E., Bhavane, R., Tasciotti, E., Chiappini, C., Liu, X., Tanaka, T., Decuzzi, P. and Ferrari, M. (2010). Tailoring the degradation kinetics of mesoporous silicon structures through PEGylation. J Biomed Mater Res A 94(4): 1236-1243.
  19. Tanaka, T., Mangala, L. S., Vivas-Mejia, P. E., Nieves-Alicea, R., Mann, A. P., Mora, E., Han, H. D., Shahzad, M. M., Liu, X., Bhavane, R., Gu, J., Fakhoury, J. R., Chiappini, C., Lu, C., Matsuo, K., Godin, B., Stone, R. L., Nick, A. M., Lopez-Berestein, G., Sood, A. K. and Ferrari, M. (2010). Sustained small interfering RNA delivery by mesoporous silicon particles. Cancer Res 70(9): 3687-3696.
  20. Tanaka, T., Godin, B., Lee, S. Y., Kott, M., Ewing, A., Deccuzi, P. and Ferrari, M. (2010). A scaling law for the vasculature adhesion of blood borne particles. Journal of Controlled Release 15;141(3):320-7.
  21. Mangala, L. S., Zuzel, V., Schmandt, R., Leshane, E. S., Halder, J. B., Armaiz-Pena, G. N., Spannuth, W. A., Tanaka, T., Shahzad, M. M., Lin, Y. G., Nick, A. M., Danes, C. G., Lee, J. W., Jennings, N. B., Vivas-Mejia, P. E., Wolf, J. K., Coleman, R. L., Siddik, Z. H., Lopez-Berestein, G., Lutsenko, S. and Sood, A. K. (2009). Therapeutic Targeting of ATP7B in Ovarian Carcinoma. Clin Cancer Res 15(11): 3770-3780.
  22. Tanaka, T. and De Luca, L. M. (2009). Therapeutic potential of "rexinoids" in cancer prevention and treatment. Cancer Res 69(12): 4945-4947.
  23. Tanaka, T., Decuzzi, P., Cristofanilli, M., Sakamoto, J. H., Tasciotti, E., Robertson, F. M. and Ferrari, M. (2009). Nanotechnology for breast cancer therapy. Biomed Microdevices 11(1): 49-63.
  24. TTanaka, T., Suzuki, A., Kuranuki, S., Mochizuki, K., Suruga, K., Takase, S. and Goda, T. (2008). Higher expression of jejunal LPH gene in rats fed the high-carbohydrate/low-fat diet compared with those fed the low-carbohydrate/high-fat diet is associated with in vitro binding of Cdx-2 in nuclear proteins to its promoter regions. Life Sci 83(3-4): 122-127.
  25. Tanaka, T., Suh, K. S., Lo, A. M. and De Luca, L. M. (2007). p21WAF1/CIP1 is a common transcriptional target of retinoid receptors: pleiotropic regulatory mechanism through retinoic acid receptor (RAR)/retinoid X receptor (RXR) heterodimer and RXR/RXR homodimer. J Biol Chem 282(41): 29987-29997.
  26. Kuranuki, S., Mochizuki, K., Tanaka, T. and Goda, T. (2007). The possible roles of homeobox protein, Cdx-2 for the expression of LPH gene during postnatal development. Life Sci 80(8): 795-799.
  27. Suh, K. S., Crutchley, J. M., Koochek, A., Ryscavage, A., Bhat, K., Tanaka, T., Oshima, A., Fitzgerald, P. and Yuspa, S. H. (2007). Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers. Clin Cancer Res 13(1): 121-131.