联合作者(
Chengwen Li University of North Carolina at Chapel Hill
1 protocol

Zheng Chai Gene Therapy Center, University of North Carolina, Orange, Orange,
1 protocol

R. Jude Samulski
研究方向
  • 免疫学
  • 已发表 protocol 1
已发表 protocol 1篇
Nab Escaping AAV Mutants Isolated from Mouse Muscles
从小鼠肌肉中分离Nab逃脱AAV突变体

作者:Zheng Chai, R. Jude Samulski and Chengwen Li日期:05/05/2018,浏览量:4888,Q&A: 0
Neutralizing antibodies (Nabs) are a major challenge in clinical trials of adeno-associated virus (AAV) vector gene therapy, because Nabs are able to inhibit AAV transduction in patients. We have successfully isolated several novel Nab-escaped AAV ...