联合作者(
Walter Sandtner Department of Pharmacology, Medical University of Vienna, Austria, Austria,
1 protocol

Verena Burtscher Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Austria, Austria,
1 protocol

Matej Hotka
  • Department of Pharmacology, Medical University of Vienna, Austria, Austria,
研究方向
  • 生物物理学
  • 已发表 protocol 1

Education

PhD., Pavol Jozef Safarik University, Kosice, Slovakia

Current position

Postdoctoral research fellow, Division of Neurophysiology and Neuropharmacology, Institute of Pharmacology, Medical University of Vienna, Austria

Publications

  1. Burtscher V, Hotka M, Li Y, Freissmuth M, Sandtner W. A label-free approach to detect ligand binding to cell surface proteins in real time. Elife. 2018 Apr 26;7. pii: e34944. doi: 10.7554/eLife.34944. 
  2. Hoťka M, Zahradník I. (2017). Reconstruction of membrane current by deconvolution and its application to membrane capacitance measurements in cardiac myocytes. PLoS One. Nov 22;12(11):e0188452. 
  3. Stiglbauer V, Hotka M, Ruiß M, Hilber K, Boehm S, Kubista H. (2017). Ca(v) 1.3 channels play a crucial role in the formation of paroxysmal depolarization shifts in cultured hippocampal neurons. Epilepsia. May;58(5):858-871. 
  4. Macková K, Zahradníková A Jr, Hoťka M, Hoffmannová B, Zahradník I, Zahradníková A. (2017). Calcium release-dependent inactivation precedes formation of the tubular system in developing rat cardiac myocytes. Eur Biophys J. Dec;46(8):691-703. 
  5. Janicek R, Hotka M, Zahradníková A Jr, Zahradníková A, Zahradník I. (2013). Quantitative analysis of calcium spikes in noisy fluorescent background. PLoS One. 2013 May 31;8(5):e64394.
已发表 protocol 1篇
Detection of Ligand-binding to Membrane Proteins by Capacitance Measurements
通过电容测量来测定膜蛋白的配体结合

作者:Verena Burtscher, Matej Hotka and Walter Sandtner日期:01/05/2019,浏览量:4060,Q&A: 0
In multi-cellular organisms, cells communicate with each other utilizing chemical messengers. For many of these messenger molecules, the membrane is an insurmountable barrier. Yet, they act by binding to surface proteins often triggering a cascade ...