联合作者(
Olga S. Koutsoni Laboratory of Cellular Immunology & National Reference Laboratory for Leishmaniasis, Department of Microbiology, Hellenic Pasteur Institute, Greece
2 protocols

Kalliopi V. Karampetsou Laboratory of Cellular Immunology & National Reference Laboratory for Leishmaniasis, Department of Microbiology, Hellenic Pasteur Institute, Greece
2 protocols

Eleni Dotsika
  • Research Director, Laboratory of Cellular Immunology & National Reference Laboratory for Leishmaniasis, Department of Microbiology, Hellenic Pasteur Institute, Greece
研究方向
  • -
  • 已发表 protocol 2

教育背景

Ph.D in Medicine, Department of Pathology, The Medical School, University of Bristol, UK, 1984

发表论文

Since 2010
• Koutsoni, O., Barhoumi, M., Karabetsou, K., Guizani, I. and Dotsika E. (2016). Assessment of potential adjuvanticity of recombinant Leishmania infantum eukaryotic initiation factor in a murine model. J Bacteriol Parasitol, 7:3
• Kyriazis, I. D., O.S. Koutsoni, N. Aligiannis, K. Karampetsou, A. L., Skaltsounis and E. Dotsika. (2016). The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes. Parasit Vectors. 9(1):441.
• Tseveleki, V., Tselios, T., Kanistras, I., Koutsoni, O., Karamita, M., Vamvakas, S. S., Apostolopoulos, V., Dotsika, E., Matsoukas, J., Lassmann, H. and Probert, L. (2015). Mannan-conjugated myelin peptides prime non-pathogenic Th1 and Th17 cells and ameliorate experimental autoimmune encephalomyelitis. Exp Neurol 267: 254-267.
• Agallou M., Dotsika E. and Karagouni E. (2014). Low CD40 expression levels in Leishmania infantum-infected bone marrow dendritic cells evokes regulatory responses by down-regulating IL-12 production: Role of ERK1/2. Eur. J. Inflammation. 12(2): 315-328.
• Agallou, M., Dotsika, E., Frydas, S. and Karagouni, E. (2014). Toll-like receptor 4 promotes control of Leishmania infantum infection through inducement of leishmanicidal activity in host macrophages: role of mitogen activated kinases. J Biol Regul Homeost Agents 28(1): 41-52.
• Agallou, M., Athanasiou, E., Koutsoni, O., Dotsika, E. and Karagouni, E. (2014). Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins. Front Immunol 5: 268.
• Koutsoni, O., Barhoumi, M., Guizani, I. and Dotsika, E. (2014). Leishmania eukaryotic initiation factor (LeIF) inhibits parasite growth in murine macrophages. PLoS One 9(5): e97319.
• Kyriazis, J. D., Aligiannis, N., Polychronopoulos, P., Skaltsounis, A. L. and Dotsika, E. (2013). Leishmanicidal activity assessment of olive tree extracts. Phytomedicine 20(3-4): 275-281.
• Kyriazis, J. D., Aligiannis, N., Polychronopoulos, P., Skaltsounis, A. L. and Dotsika, E. (2013). Leishmanicidal activity assessment of olive tree extracts. Phytomedicine 20(3-4): 275-281.
• Papagiannopoulos, I. A., Sideris, V. I., Boschmann, M., Koutsoni, O. S. and Dotsika, E. N. (2013). Anthropometric, hemodynamic, metabolic, and renal responses during 5 days of food and water deprivation. Forsch Komplementmed 20(6): 427-433.
• Rigos, G., Fountoulaki ,E., Cottou, E., Dotsika, E., Dourala, N. and Karacostas I. (2013). Tissue distribution and field evaluation of caprylic acid against natural infections of Sparicotyle chrysophrii in cage-reared gilthead sea bream Sparus aurata. Aquaculture 408-409:15-19.
• Koutsoni, Ο., Barhoumi, M., Guizani, I. and E. Dotsika. (2011). LiEIF and its recombinant polypeptides enhance the maturation of mouse dendritic cells and the production of the protective IL-12 cytokine. BMC proceedings 01/2011; 5:1-1.
• Tsatchev, I., I. D. Kyriazis, S. Boutsini, E. Karagouni and E. Ν. Dotsika. (2010). First Report of canine visceral leishmaniasis in Bulgaria. Turkish J. Vet. Anim. Science 34(3):1-5.
已发表 protocol 2篇
Quantification of Nitric Oxide and Reactive Oxygen Species in Leishmania-infected J774A.1 Macrophages as a Response to the in vitro Treatment with a Natural Product Compound
感染利什曼原虫J774A.1的巨噬细胞响应体外天然化合物处理的一氧化氮和活性氧定量分析

作者:Kalliopi Karampetsou, Olga S. Koutsoni and Eleni Dotsika日期:12/05/2019,浏览量:2134,Q&A: 0
Leishmaniasis is a parasitic disease caused by the obligatory intracellular protozoa Leishmania spp. Current therapeutic options are limited and thus, drug discovery against leishmaniasis is very important. Nevertheless, there is a great ...
In vitro Screening of Antileishmanial Activity of Natural Product Compounds: Determination of IC50, CC50 and SI Values
天然复合产物抗利什曼原虫活性的体外筛选:IC50、CC50和SI值的测定

作者:Olga S. Koutsoni, Kalliopi Karampetsou and Eleni Dotsika日期:11/05/2019,浏览量:2467,Q&A: 0
Neglected tropical diseases gain the scientific interest of numerous research programs in an attempt to achieve their effective control or elimination. In this attempt, more cutting-edge public health policies and research are needed for the ...