联合作者(
Wael Jarjour Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol

Lai Chu Wu Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol

Caitlin Henry Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol

William L. Willis Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol

Abigail Foster
  • Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
研究方向
  • 生物化学
  • 已发表 protocol 1
已发表 protocol 1篇
In vitro Crosslinking Reactions and Substrate Incorporation Assays for The Identification of Transglutaminase-2 Protein Substrates
转谷氨酰胺酶-2蛋白底物的体外交联反应和底物掺入鉴定

作者:William L. Willis, Abigail Foster, Caitlin Henry, Lai Chu Wu and Wael Jarjour日期:06/20/2020,浏览量:1766,Q&A: 0
Transglutaminase (TG2) catalyzes protein crosslinking between glutamyl and lysyl residues. Catalytic activity occurs via a transamidation mechanism resulting in the formation of isopeptide bonds. Since TG2-mediated transamidation is of mechanistic ...