联合作者(
David Julian Mann Life Sciences Imperial College London
1 protocol

Gregory Benedict Craven Chemical Biology University of Leeds
1 protocol

Alan Armstrong
  • Professor, Department of Chemistry Imperial College London
研究方向
  • Chemistry, chemical biology
  • 已发表 protocol 1

教育背景

PhD, Imperial College London

发表论文

https://scholar.google.com/citations?user=9K1Xbo0AAAAJ&hl=en
已发表 protocol 1篇
Quantitative Irreversible Tethering (qIT) for Target-directed Covalent Fragment Screening
用于靶标定向共价片段筛选的定量不可逆系链(qIT)

作者:Gregory B. Craven, David J. Mann and Alan Armstrong日期:12/20/2020,浏览量:1079,Q&A: 0

Small molecules that react to form covalent bonds with proteins are widely used as biological tools and therapeutic agents. Screening cysteine-reactive fragments against a protein target is an efficient way to identify chemical starting points for

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