联合作者(
Darren R. Carpizo University of Rochester School of Medicine and Dentistry Rochester
1 protocol

Xin Yu Rutgers Cancer Institute of New Jersey New Brunswick
1 protocol

Jeung- Hoi Ha Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
1 protocol

Stewart N. Loh
  • Faculty, Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
研究方向
  • 已发表 protocol 1
已发表 protocol 1篇
Urea Denaturation, Zinc Binding, and DNA Binding Assays of Mutant p53 DNA-binding Domains and Full-length Proteins
突变p53 DNA结合域和全长蛋白的尿素变性、锌结合和DNA结合分析

作者:Jeung-Hoi Ha, Xin Yu, Darren R. Carpizo and Stewart N. Loh日期:10/20/2021,浏览量:531,Q&A: 0

In the cell, the thermodynamic stability of a protein – and hence its biological activity – can change dramatically as a result of perturbations in its amino acid sequence and the concentration of stabilizing ligands. This interplay is

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