细胞生物学

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    现刊
    Lentiviral Barcode Labeling and Transplantation of Fetal Liver Hematopoietic Stem and Progenitor Cells
    胎儿肝脏造血干细胞和祖细胞的慢病毒条形码标记和移植
    作者:Trine A. Kristiansen, Alexander Doyle and Joan Yuan日期:04/20/2017,浏览量:8044,Q&A: 0
    [Abstract] Cellular barcoding enables the dissection of clonal dynamics in heterogeneous cell populations through single cell lineage tracing. The labeling of hematopoietic stem and progenitor cells (HSPCs) with unique and heritable DNA barcodes, makes it possible to resolve donor cell heterogeneity in terms of differentiation potential and lineage bias at ...