系统生物学

Advertisement

分类

    现刊
    Quantifying Symmetrically Methylated H4R3 on the Kaposi’s Sarcoma-associated Herpesvirus (KSHV) Genome by ChIP-Seq
    采用ChIP-Seq定量卡波西肉瘤相关疱疹病毒(KSHV)基因组上的对称甲基化H4R3
    作者:Roxanne C. Strahan, Kayla S. Hiura and Subhash C. Verma日期:03/20/2018,浏览量:6189,Q&A: 0
    [Abstract] Post-translational modifications to histone tails contribute to the three-dimensional structure of chromatin and play an important role in determining the relative expression of nearby genes. One such modification is symmetric di-methylation of arginine residues, which may exhibit different effects on gene expression including blocking the binding ...
    Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data
    利用ChIP-seq数据分析药物诱导小鼠大脑中染色质修饰发生改变的生物信息学方法
    作者:Yong-Hwee Eddie Loh, Jian Feng, Eric Nestler and Li Shen日期:02/05/2017,浏览量:9815,Q&A: 0
    [Abstract] Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a powerful technology to profile genome-wide chromatin modification patterns and is increasingly being used to study the molecular mechanisms of brain diseases such as drug addiction. This protocol discusses the typical procedures involved in ChIP-seq data ...