Education
Ph.D. in Life Sciences, Open University, UK
Sponsoring establishments: “Mario Negri Sud" Institute and Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, 2011
Current position
Researcher, Institute of Protein Biochemistry, National Research Council, Naples, Italy
Publications
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Valente, C., Luini, A. and Corda, D. (2013). Components of the CtBP1/BARS-dependent fission machinery. Histochem Cell Biol 140(4): 407-421.
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Colanzi, A., Grimaldi, G., Catara, G., Valente, C., Cericola, C., Liberali, P., Ronci, M., Lalioti, V. S., Bruno, A., Beccari, A. R., Urbani, A., De Flora, A., Nardini, M., Bolognesi, M., Luini, A. and Corda, D. (2013). Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS. Proc Natl Acad Sci U S A 110(24): 9794-9799.
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D'Apice, L., Costa, V., Valente, C., Trovato, M., Pagani, A., Manera, S., Regolo, L., Zambelli, A., Ciccodicola, A. and De Berardinis, P. (2013). Analysis of SEMA6B gene expression in breast cancer: identification of a new isoform. Biochim Biophys Acta 1830(10): 4543-4553.
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Valente, C., Turacchio, G., Mariggio, S., Pagliuso, A., Gaibisso, R., Di Tullio, G., Santoro, M., Formiggini, F., Spano, S., Piccini, D., Polishchuk, R. S., Colanzi, A., Luini, A. and Corda, D. (2012). A 14-3-3gamma dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIbeta to regulate post-Golgi carrier formation. Nat Cell Biol 14(4): 343-354.
*Classified by the Faculty of 1000 in the top 2% of papers published in 2012 in medicine and biology
*Classified by the Italian Association for Cancer research (AIRC) as one of the top 10 papers published from projects financed by AIRC in 2012
*Classified by the Italian National Research Council as one of the published highlights of 2011/2012
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Yang, J. S., Valente, C., Polishchuk, R. S., Turacchio, G., Layre, E., Moody, D. B., Leslie, C. C., Gelb, M. H., Brown, W. J., Corda, D., Luini, A. and Hsu, V. W. (2011). COPI acts in both vesicular and tubular transport. Nat Cell Biol 13(8): 996-1003.
*Classified by the Italian National Research Council as one of the published highlights of 2010/2011
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Valente, C., Polishchuk, R. and De Matteis, M. A. (2010). Rab6 and myosin II at the cutting edge of membrane fission. Nat Cell Biol 12(7): 635-638.
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Nardini, M., Valente, C., Ricagno, S., Luini, A., Corda, D. and Bolognesi, M. (2009). CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization. Biochem Biophys Res Commun 381(1): 70-74.
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Yang, J. S., Gad, H., Lee, S. Y., Mironov, A., Zhang, L., Beznoussenko, G. V., Valente, C., Turacchio, G., Bonsra, A. N., Du, G., Baldanzi, G., Graziani, A., Bourgoin, S., Frohman, M. A., Luini, A. and Hsu, V. W. (2008). A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance. Nat Cell Biol 10(10): 1146-1153.
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Liberali, P., Kakkonen, E., Turacchio, G., Valente, C., Spaar, A., Perinetti, G., Bockmann, R. A., Corda, D., Colanzi, A., Marjomaki, V. and Luini, A. (2008). The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS. EMBO J 27(7): 970-981.
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Valente, C., Spano, S., Luini, A. and Corda, D. (2005). Purification and functional properties of the membrane fissioning protein CtBP3/BARS. Methods Enzymol 404: 296-316.
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Bonazzi, M., Spano, S., Turacchio, G., Cericola, C., Valente, C., Colanzi, A., Kweon, H. S., Hsu, V. W., Polishchuck, E. V., Polishchuck, R. S., Sallese, M., Pulvirenti, T., Corda, D. and Luini, A. (2005). CtBP3/BARS drives membrane fission in dynamin-independent transport pathways. Nat Cell Biol 7(6): 570-580.
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Spano, S., Silletta, M. G., Colanzi, A., Alberti, S., Fiucci, G., Valente, C., Fusella, A., Salmona, M., Mironov, A., Luini, A. and Corda, D. (1999). Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure. J Biol Chem 274(25): 17705-17710.