Cindy Ast Cooke
  • Post-Doc, Carnegie Institution for Science
  • Biophysics


PhD, University of Potsdam


Frommer Lab


Fluorescent Proteins, Biosensors, Spectroscopy, Microscopy


Ast, C., Foret, J., Oltrogge, L.M., De Michele, R., Kleist, T.J., Ho, C.-H., and Frommer, W.B. Ratiometric Matryoshka biosensors from a nested cassette of green- and orange-emitting fluorescent proteins. Nat Commun (2017).
Ast, C., De Michele, R., Kumke, M. U. & Frommer, W. B. Single-fluorophore membrane transport activity sensors with dual-emission read-out. eLife 4, (2015).
Ast, C., Frommer, W. B., Grossmann, G. & De Michele, R. Quantification of Extracellular Ammonium Concentrations and Transporter Activity in Yeast Using AmTrac Fluorescent Sensors. Bio-Protoc. 5, e1372 (2015).
Ast, C. & Draaijer, A. in Low-Oxygen Stress in Plants (eds. Dongen, J. T. van & Licausi, F.) 397–417 (Springer Vienna, 2014).
Haupt, J. et al. ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant. Hum. Mol. Genet. 23, 5364–5377 (2014).
De Michele, R. et al. Fluorescent sensors reporting the activity of ammonium transceptors in live cells. eLife 2, e00800 (2013).
Wang, Q. et al. Single-particle analysis reveals shutoff control of the Arabidopsis ammonium transporter AMT1;3 by clustering and internalization. Proc. Natl. Acad. Sci. U. S. A. 110, 13204–13209 (2013).
Ast, C., Schmälzlin, E., Löhmannsröben, H.-G. & van Dongen, J. T. Optical oxygen micro- and nanosensors for plant applications. Sensors 12, 7015–7032 (2012).
Hill, D. et al. Size determination of quantum dots with fluorescence correlation spectroscopy. in (eds. Parak, W. J., Yamamoto, K. & Osinski, M.) 790904 (2011). doi:10.1117/12.874660
Shen, Q. et al. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J. Clin. Invest. 119, 3462–3472 (2009).