Isabelle Colas
  • Research scientist, James Hutton Institute
  • Plant science






Control of Meiosis and Recombination in Cereals


• Isabelle Colas, Luke Ramsay and Robbie Waugh. Barley meiosis: The importance of sticking together. Published in Atlas of Sciences 7th March 2017.
• Isabelle Colas, Malcolm Macaulay, James D. Higgins, Dylan Phillips, Abdellah Barakate, Markus Posch, Sue J. Armstrong, F. Chris H. Franklin, Claire Halpin, Robbie Waugh, and Luke Ramsay. A spontaneous mutation in MutL-Homolog 3 (HvMLH3) affects synapsis progression and crossover resolution in the barley desynaptic mutant des10. (2016) New Phytol. 212(3):693-707
• Isabelle Colas, Kathie Baker and Andrew J. Flavell. Cytology and Microscopy: Immunolocalization of Covalently Modified Histone Marks on Barley Mitotic Chromosomes. (2016) Bio-protocol 6(12): e1841. http://www.bio-protocol.org/e1841
• Katie Baker, Taniya Dhillon, Isabelle Colas, Nicola Cook, Iain Milne, Linda Cardle, Micha Bayer, and Andrew J. Flavell. Chromatin state analysis of the barley epigenome reveals an ultrastructure defined by H3K27me1 and H3K27me3 abundance. (2015) The Plant Journal 84:111-124.
• Dylan Phillips, Glyn Jenkins, Malcolm Macaulay, Candida Nibau, Joanna Wnetrzak, Derek Fallding, Isabelle Colas, Helena Oakey, Robbie Waugh, Luke Ramsay. The effect of temperature on the male and female recombination landscape of barley. New Phytologist. 2015 7 AUG 2015 DOI: 10.1111/nph.13548
• Luke Ramsay, Isabelle Colas and Robbie Waugh: Modulation of Meiotic Recombination. Biotechnological Approaches to Barley Improvement, Biotechnology in Agriculture and Forestry ed Kumlehn JS, N. 2014, Vol 69, pp 311-319
• Baker K, Bayer M, Cook N, Dreißig S, Dhillon T, Russell J, Hedley PE, Morris J, Ramsay L, Colas I, Waugh R, Steffenson B, Milne I, Stephen G, Marshall D, Flavell AJ. The low-recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression. Plant J. 2014 Sep;79(6):981-992
• Barakate A, Higgins JD, Vivera S, Stephens J, Perry RM, Ramsay L, Colas I, Oakey H, Waugh R, Franklin FC, Armstrong SJ, Halpin C. The synaptonemal complex protein ZYP1 is required for imposition of meiotic crossovers in barley. Plant Cell. 2014 Feb;26(2):729-40.
• Emma Greer, Azahara Martinez-Ramirez, Ali Pendle, Isabelle Colas, Alex Jones, Graham Moore and Peter Shaw. The Ph1 Locus Suppresses Cdk2-Type Activity during Premeiosis and Meiosis in Wheat. Plant Cell. 2012 Jan; 24(1): 152–162.
• Colas, I., Koroleva, O. and Shaw, P.J. Mass spectrometry in plant proteomic analysis. Plant Biosystems 2010 144(3), 703-714.
• Isabelle Colas, Peter Shaw, Pilar Prieto, Michael Wanous, Wolfgang Spielmeyer, Rohit Mago and Graham Moore. Effective chromosome pairing requires chromatin remodelling at the onset of meiosis. PNAS 2008 105(16): 6075–6080
• Griffith S., Sharp R., Foote T.N., Bertin I., Wanous M., Reader S, Colas I., Moore G. Molecular characterization of Ph1 as a major chromosome pairing locus in polyploid wheat. Nature 2006 439:749-752